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Colon Intestine Articles & Analysis

5 articles found

Accurately Recapitulating Environmental Niches in  Vitro Models of the Intestine

Accurately Recapitulating Environmental Niches in Vitro Models of the Intestine

Intestinal stem cells divide rapidly, continually replacing differentiated cells which, in the human colon, live only around five days. ...

ByAltis Biosystems


Enhancing Human Gut Tissue Models through Gene Editing

Enhancing Human Gut Tissue Models through Gene Editing

The RepliGut® platform produces a polarized monolayer of human intestinal stem and differentiated cells — either of the large or small intestine — that can be used for modeling diseases or screening compounds for effects on the intestine. ...

ByAltis Biosystems


Evaluating Microbiome Therapies with Intestinal Cell Models

Evaluating Microbiome Therapies with Intestinal Cell Models

Intestinal and Colonic Stem Cells and Disease Stem cells are implicated in a variety of disease process. ...

ByAltis Biosystems


Cutaneous Patches to Monitor Myoelectric Activity of the Gastrointestinal Tract in Postoperative Pediatric Patients

Cutaneous Patches to Monitor Myoelectric Activity of the Gastrointestinal Tract in Postoperative Pediatric Patients

Rhythmic signals of the stomach, small intestine, and colon could be identified in all three subjects. Patients showed gradual increase in myoelectric intestinal and colonic activity leading up to the first recorded bowel movement. Conclusion: Measuring myoelectric intestinal activity continuously using a ...

ByG-Tech Medical


Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice

Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice

Mice carrying Apc mutations in their germ line (ApcMin) develop intestinal adenomas. Here, the crossing of ApcMin with cyclin D1–/– mice reduced the intestinal tumor number in animals genetically heterozygous or nullizygous for cyclin D1. Decreased tumor number in the duodenum, intestines, and colons of ApcMin/cyclin D1+/– mice ...

ByAmerican Society for Microbiology (ASM)

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