Compound Library Articles & Analysis
4 articles found
Due to all the previously described advantages presented by the zebrafish animal model, it has recently come to the fore in the drug discovery process (i) to identify molecules that specifically ameliorate disease phenotypes and (ii) to conduct detailed characterization studies around optimizing compounds with a focus not only on efficacy ( dose-response), but also in toxicity ...
Traditionally, the identification of prospective drug candidates necessitated resource-intensive and time-consuming experimental screenings of extensive compound libraries. Virtual screening has transcended this paradigm by expediting the identification process through computational analysis, allowing researchers to swiftly identify compounds ...
Virtual screening is a computer-based methodology that harnesses advanced algorithms and predictive models to analyze vast chemical libraries. It enables scientists to identify promising compounds for drug development without physically testing each one. ...
In parallel synthesis, individual molecules are synthesized in a spatially addressable format and these compounds can be screened similar to individual compounds made by medicinal chemists. Relying heavily on automation for leverage, this approach can generate many more compounds compared to the traditional “one at a time” approach ...