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Computational Systems Biology Articles & Analysis
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The development of new and effective drugs is a complex and multifaceted process that requires the collaboration of scientists from diverse fields, including chemistry, biology, and computational modeling. At the heart of this endeavor lies the art of drug design - the strategic and methodical approach to creating molecules that can effectively target and ...
The process of drug discovery is a complex and multifaceted endeavor, involving the integration of diverse scientific disciplines, including biology, chemistry, and computational science. At the heart of this endeavor lies the intricate relationship between drugs, their targets, and the diseases they aim to treat. ...
In the dynamic realm of drug discovery, the pursuit of innovative and effective treatments for diverse diseases demands groundbreaking approaches that can expedite the drug development lifecycle. Amidst these endeavors, Computer-Aided Drug Design (CADD) has emerged as a transformative methodology, harnessing the power of computational tools and simulations to predict, understand, and optimize the ...
In the realm of modern medicine, the quest for new and effective drugs to combat various diseases is a continuous journey. Drug discovery, the process of identifying compounds that can potentially treat diseases, has seen a significant transformation in recent years, thanks to advancements in computational biology and artificial intelligence (AI). In this article, we will delve into the ...
The Perinatology Research Branch (PRB) is the only Clinical Branch in the Division of Intramural Research (DIR) of the National Institutes of Health (NIH) to focus its research on human pregnancy and unborn children. It is currently housed at the Detroit Medical Center in Detroit, Michigan through a service contract. The Branch has thrived in this environment, earning a national and international ...
Pancreatic cancer is a highly malignant digestive system tumor, and the five-year survival rate of patients after diagnosis is only about 10%. ...
Some of my earliest memories are of accompanying her to medical school classes, which inspired me to eventually pursue a PhD in molecular biology and biochemistry. My studies brought me to the U.S., where my interests shifted towards computer science and after school, I landed a role where I could apply both my software engineering and molecular ...
I was born in a country at the intersection of Europe and the Middle East — both geographically and culturally. Turkey is a beautiful country, and also a challenging one in many aspects. My mom was not able to continue her education after fifth grade because the middle school for girls was miles away from her home. She has always been a big supporter of my education and career. Growing ...
Throughout my career, I always heard about finding your “dream job” but had honestly dubbed the concept a myth. I never imagined that one day, that myth would become my reality. On April 5th, 2021 my now-manager Ben Sukow called with a job offer that changed my perspective. For almost a decade, I have wanted to work in the field of computational biology. I wanted to learn and grow ...
A study of Universal Diagnostics' blood-based colorectal cancer test found it was more than 90 percent accurate, the company announced June 3. The blood test was found to detect colorectal cancer with 92 percent sensitivity and 97 percent specificity. It also was shown to have 89 percent sensitivity and 97 percent specificity detecting early-stage cancer. The test uses single target sequence ...
Having originally trained as an engineer biochemist, Parag's research is diverse and spans computational and experimental systems biology, cancer biology, and nanotechnology. ...
Malaria is a vector-borne infectious disease caused by protozoan parasite of the genus Plasmodium. The malaria vaccine which has been studied is designed to induce immunity to the sporozoite and to kill sporozoite-infected liver cells. A combination of bioinformatics approach and computational tools are used to screen and select antigen sequences as potential T-cell epitopes of supertype human ...