Demyelination Articles & Analysis
2 articles found
Dysregulated LPA signaling has been linked to neuropathic pain, neuroinflammation, and demyelinating conditions, positioning ENPP2 as a key player in neural health and disease. ...
In the central nervous system, myelin is generated by oligodendrocytes, which are differentiated from oligodendrocyte precursor cells (OPC). In some demyelinating diseases, such as multiple sclerosis and white matter lesions, there are many OPCs in the lesion, but they cannot differentiate into mature oligodendrocytes, and our understanding of OPC differentiation to myelinate is ...