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Diabetes Mellitus Articles & Analysis
18 articles found
Dysbiosis of the intestinal flora is associated with a variety of human metabolic diseases, such as obesity, diabetes mellitus, and nonalcoholic fatty liver disease. Regulation of lipoprotein metabolism by intestinal flora The intestine is not only a site of lipid digestion and absorption, but also a place where a large number of microorganisms reside. ...
Diabetes, specifically Type 1 and Type 2 Diabetes Mellitus, remains one of the most commonly encountered metabolic diseases worldwide. ...
HFpEF patients are likely to have a high prevalence of cardiovascular and non-cardiovascular comorbidities, such as obesity, metabolic syndrome, diabetes mellitus type 2, salt-sensitive hypertension, atrial fibrillation (AF), chronic obstructive pulmonary disease, anaemia, and renal dysfunction.[6.7,8] As life expectancy and comorbidity rates rise, the ...
HFpEF is a complex disease which accounts for more than half of all heart failure (HF) hospital admissions and is an increasing disease burden. [1] The prevalence of HFpEF is climbing, reflecting an increasingly elderly and comorbid population, as well as reinforcing the need for more effective therapies.[2] SGLT2is are a class of anti-diabetic drugs that have demonstrated large ...
This condition may be due age or might be due some chronic conditions like Diabetes mellitus (DM) or chronic kidney disease (CKD). Extreme muscle wasting often results in weight loss. ...
Variants in HLA genes are now thought to increase susceptibility to a variety of immune-mediated diseases, such as rheumatoid arthritis and diabetes mellitus type 1. Rapid advances in sequencing technology have changed the way of querying the role of HLAs in clinical and basic studies. ...
Introduction Metabolic syndrome (MetS) is a group of clinical conditions manifested as abdominal obesity, hyperglycemia, hypertension, dyslipidemia, and chronic inflammation, concurrently leading to a marked increase in the risk of heart disease, diabetes, and stroke, or all three (1, 2). Currently, MetS is a growing health concern due to its increasing prevalence globally (3). ...
ABILITY Diabetes Global (Randomized Comparison of Abluminus DES+ Sirolimus-Eluting Stents versus Everolimus-Eluting Stents in Coronary Artery Disease Patients with Diabetes Mellitus Global) started off with the index patient enrolment on 11th June 2020 in Italy (at the peak of the 1st wave of COVID-19 pandemic) by P.I. ...
Case Presentation A 58-year-old male with a history of hypertension, diabetes mellitus, and prostate cancer was admitted for a video-assisted thoracoscopic surgery (VATS) esophagectomy. ...
A successful example is the DPP4 inhibitors (for example saxagliptin and vildagliptin) for the treatment of diabetes mellitus type 2. In addition, there is Odancate, which is used for the treatment of osteoporosis in postmenopausal women. ...
They may have a lot of comorbidities—such as diabetes, chronic kidney disease, end-stage renal disease—and they’re complex cases. ...
After adjustments for age, sex, BMI, diabetes mellitus, and cirrhosis using multivariate association with linear models (MaAsLin),RuminococcaceaeandVeillonellaceaeare the main microbial taxa associated with significant fibrosis in non-obese subjects. ...
Our goal was that by integrating clinical risk factors known to influence clopidogrel response (age, body mass index, Chronic Kidney Disease, and Diabetes Mellitus) with the CYP2C19 genetic factor into a score, we can improve the precision of guided de-escalation for P2Y12 inhibitor therapy such that this can be safely performed in “real-world” ...
The increasing incidence of peripheral artery disease (PAD) is occurring globally as populations age and rates of diabetes, obesity, and renal disease increase.1-3 Although most of these patients have no symptoms, when the disease progresses to its most advanced form, chronic limb-threatening ischemia (CLTI), there is a significant risk for limb loss. ...
This case study discusses hospital readmissions and provides healthcare professionals with recommended medical algorithms in the form of scores, models, and calculators that can aid in reducing readmissions, especially when related to antibiotic resistant microbiological pathogens. When health analytics, such as the CDC antibiotic resistance program and other algorithms are integrated into ...
Insulin controls glucose homeostasis and lipid metabolism, and insulin impairment plays a critical role in the pathogenesis of diabetes mellitus. Human skeletal muscle and kidney enriched inositol polyphosphate phosphatase (SKIP) is a member of the phosphatidylinositol 3,4,5-trisphosphate phosphatase family (T. ...
We examined the effect of X-irradiation (0, 0.25, 0.5 or 1.0 Gy) on the onset of the type I diabetes (insulin dependent diabetes mellitus) in non-obese diabetic (NOD) mice. ...
The diagnosis of clinically mute diabetes mellitus (DM) is based on a nominal concentration of fasting peripheral venous plasma glucose (f-vPG) at ≥7.0mmol/l, to be exceeded by first and confirmatory measurement. ...