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Drug Delivery Coatings System Articles & Analysis
78 articles found
In the fast-evolving field of antibody–drug conjugates (ADCs), linker chemistry plays a decisive role in defining therapeutic performance. The ability to control the drug-to-antibody ratio (DAR), conjugation site, and overall molecular stability directly impacts both efficacy and safety. Among emerging linker materials, azide-functionalized PEG derivatives have become essential tools for ...
Precise and safe delivery of drugs to target sites has always been an important task for researchers in modern medicine. With the development of nanotechnology, a variety of nanodrug delivery systems (NDDS) have been designed and prepared, such as the most familiar liposomes, polymer nanoparticles, and metal nanoparticles. However, a new kind of drug delivery system has also gradually emerged in ...
Virus-like particles (VLPs) have garnered significant attention in recent years for their potential applications in vaccine development, drug delivery, and as tools in various biotechnological fields. These nanoparticles mimic the structure of viruses but lack the viral genetic material that makes viruses infectious. This unique characteristic offers a versatile platform for various innovative ...
Lipid synthesis is an integral process within biochemistry that contributes to a myriad of biological functions, including energy storage, cell membrane formation, and signaling pathways. As researchers delve deeper into the complexities of lipid biology, the demand for precise and efficient lipid synthesis techniques has become increasingly evident. This article explores the various methods ...
As treatment strategies advance researchers regularly update drug delivery systems. Traditional drug delivery systems consist of liposomes and polymer micelles together with nanoparticles but despite their inclusion in clinical trials current versions still encounter limitations. ...
The MDCK permeability assay is a critical technique employed in pharmacology and drug development to evaluate the permeability of drug candidates across epithelial cell layers. This assay utilizes Madin-Darby Canine Kidney (MDCK) cells, which are a widely used model for studying intestinal absorption and permeability due to their similarity to human epithelial cells. Importance of the MDCK ...
This property, known as bioactivity, makes it an ideal material for a wide range of medical applications, including bone repair, dental restoration, and even drug delivery. Composition and Properties Bioglass is primarily composed of silica (SiO2), sodium oxide (Na2O), calcium oxide (CaO), and phosphorus pentoxide (P2O5). ...
ByMatexcel
It is widely used in bone grafts, dental implants, and coatings for orthopedic devices. Recent advancements focus on enhancing its performance in tissue engineering and drug delivery systems. For instance, HA-based scaffolds are being developed to promote bone regeneration, while HA nanoparticles are engineered to deliver ...
ByMatexcel
As the new year begins, many people prioritize their health by scheduling annual physicals and medical check-ups. While these routine exams ensure overall well-being, few realize the crucial role that fluoropolymers play in modern medical technology. From diagnostic tools to life-saving devices, fluoropolymer materials contribute significantly to patient safety, hygiene, and the accuracy of ...
The continuous advancement of biomaterials has led to the development of various copolymers, among which Poly(lactic-co-glycolic acid) (PLGA) and Polyethylene Glycol (PEG) copolymers have garnered significant attention. These materials are extensively utilized in drug delivery systems, tissue engineering, and regenerative medicine. This article presents a detailed comparison of PLGA and PEG ...
The evolution of 3D printing technology has opened up new avenues in the pharmaceutical industry, especially in the fabrication of novel drug delivery systems. One such advancement is the 3D printing of Oral Thin Films (OTFs), which are ultra-thin films used to deliver drugs via oral mucosa. ...
Exosomes, small vesicles released by cells, play an increasingly prominent role in intercellular communication and disease modulation. These nano-sized particles contain a diverse array of molecular cargo, including proteins, lipids, RNA, and metabolites, which serve as biomarkers for a variety of physiological conditions. Exosome lipidomics and metabolomics are key fields that focus on profiling ...
In the field of medical device manufacturing, the materials used in creating life-saving equipment must meet the highest standards of safety, reliability, and performance. Among these materials, fluoropolymer tubing has emerged as a critical component, playing a crucial role in various medical devices. Whether it’s for intravenous (IV) systems, catheters, or diagnostic equipment, ...
Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase, is an essential enzyme found widely in nature and recognized for its potent antimicrobial properties. First discovered by Alexander Fleming in 1922, lysozyme has been a subject of considerable scientific and commercial interest owing to its role as an effective biological defense mechanism. Commonly found in egg whites, human ...
In the rapidly evolving field of pharmaceuticals, nanotechnology has emerged as a revolutionary force, transforming the landscape of drug delivery and formulation development. The integration of nanotechnology into pharmaceutical formulation offers unprecedented opportunities to enhance the efficacy, safety, and convenience of therapeutic interventions. This article explores the profound impact ...
Nanoparticle technology in particular, Nano drug delivery system is getting a lot of attention and application in medicine in the recent years. ...
Human corneal epithelial cells play a vital role in maintaining the health and function of the cornea, the transparent front part of the eye. This layer of cells acts as a protective barrier against environmental insults, pathogens, and mechanical injury. Given their crucial functions, understanding these cells is essential for advancements in ophthalmology and regenerative medicine. The corneal ...
Copolymers are a class of polymers that consist of two or more different monomeric units. The process of creating these versatile materials is fundamental to a variety of applications in industries ranging from plastics and rubber to biomedical devices and textiles. Understanding how copolymers are made involves a grasp of the underlying chemistry, synthesis techniques, and the properties that ...
Ovalbumin, also known as albumin or OVA, is the most abundant protein found in egg white, accounting for approximately 54% of its total protein content. This versatile glycoprotein has captivated researchers and industry professionals alike due to its unique properties and wide-ranging applications. In this article, we'll explore the structure, functions, and diverse uses of ovalbumin in various ...
Polyethylene glycol (PEG) derivatives have become pivotal in the pharmaceutical industry, revolutionizing drug delivery systems and enhancing the efficacy of various therapeutic agents. The unique properties of PEG derivatives, including their biocompatibility and ability to modify the solubility, stability, and bioavailability of drugs, make them indispensable in modern pharmacology. This ...