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Drug Testing Articles & Analysis
68 articles found
Researchers can manipulate these cells genetically, test drug responses, and explore the effects of various environmental factors on ovarian health. ...
In our last blog, Peter discussed how AI is accelerating the drug discovery process and putting pressure on chemists, who must find ways of developing these potential drugs for subsequent testing or production. ...
ByBUCHI
Understanding Radioactive Drug Conjugates Radioactive drug conjugates are engineered to deliver radiation directly to cancer cells while sparing healthy tissues. ...
Creative Bioarray establishes itself as a world leader in life science innovation through its complete range of organoid services that enhance drug discovery, disease modeling, and personalized medicine. Our advanced system delivers high-quality, reproducible organoids to researchers, enabling significant advancements in their scientific work. ...
For instance, larger animals such as dogs or pigs are often preferred in the study of cardiology, while zebrafish provide a rapid assessment of pharmacokinetics and toxicity. Phases of Drug Screening Drug screening typically unfolds in several key phases: Preclinical Testing: Before any drug can enter human trials, it undergoes ...
This article explores the importance of drug screening in drug-resistant cells and its implications for advancing therapeutic strategies. ...
These cell lines serve as essential models for studying the biology of colorectal cancer, testing new therapies, and exploring the mechanisms of drug resistance. ...
High-throughput screening (HTS) has become a cornerstone of drug discovery, allowing researchers to rapidly test thousands of compounds for their ability to activate or inhibit specific nuclear receptors. ...
In the realm of pharmaceutical research and development, ADME testing services play a pivotal role in evaluating the pharmacokinetics of drug candidates. ...
Alfa Cytology has introduced its advanced drug development services for brain tumors. Alfa Cytology, celebrated for its cutting-edge biotech solutions and extensive tumor research expertise, has recently introduced brain tumor drug development services, designed to empower researchers in understanding the intricacies and unique challenges associated with brain ...
Applications: Research: Mapping the architecture and alterations in the cytoskeleton in various diseases. Drug Discovery: Observing how pharmaceuticals affect cytoskeletal integrity. ...
For example, by knocking out genes associated with diseases, scientists can better understand the roles of these genes in diseases.2. Drug DevelopmentGene knockout is also used in drug development. By knocking out drug target genes, scientists can test the effects of new drugs and potential side effects.Emerging ...
Drug antibody testing is a laboratory testing method specifically designed to evaluate the immune response of the human body to certain drugs. ...
Binding Activity Testing(1) Enzyme-Linked Immunosorbent Assay (ELISA)Uses the target antigen coated on microtiter plates to test the binding ability of the antibody drug.(2) Surface Plasmon Resonance (SPR)Can detect the binding between the antibody and the target molecule in real-time, and determine the rate constants for binding and ...
There are many different molecules in ADCs, and the difference between these molecules lies in the drug-to-antibody ratio (DAR) value and/or the site where the antibody binds to the drug. ...
Each type of nanoparticle has unique properties that can be tailored to suit specific drug delivery needs. For instance, liposomes are ideal for encapsulating hydrophilic drugs, while solid lipid nanoparticles are suitable for enhancing the bioavailability of hydrophobic drugs. ...
However, one of the challenges faced in developing small molecule drugs to treat brain cancer is the blood-brain barrier, a protective barrier that prevents many drugs from reaching their targets in the brain. Researchers are still investigating strategies to overcome this barrier, similar to the use of nanoparticles or other drug delivery ...
One of the first steps in drug development and toxicity testing is creating cell models on which to evaluate the effects of chemical compounds on cellular, molecular and biochemical processes of interests. ...
The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. ...
Our services include: Obtain basic information about drug molecules Analyze structural formula and pKa information Basic characterization of free forms Free form solubility test Choose appropriate counterions and solvents Preliminary salt form screening Scale-up preparation of advantageous salt forms Salt form assessmentStability, hygroscopicity, solubility, ...