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Drug Therapy Articles & Analysis
49 articles found
Precise and safe delivery of drugs to target sites has always been an important task for researchers in modern medicine. ...
As fibrosis develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. Current therapies for IPF rely on oral administration of pirfenidone and nintedanib, two FDA-approved drugs that slow disease progression. ...
Watertown, MA – March 24, 2025 – Biopharma PEG, a leading supplier of high-quality polyethylene glycol (PEG) derivatives, highlights its innovative product DSPE-PEG-Mannose, an advanced biomedical polymer with significant potential in drug delivery, tumor-targeted therapy, tissue recognition, and adhesion.Structural Advantages of DSPE-PEG-MannoseDSPE-PEG-Mannose ...
The classification of anti-tumor APIs often falls into four main types: chemotherapy drugs, targeted therapy drugs, immunotherapy drugs, and hormone therapy drugs. ...
These antibodies may reduce the effectiveness of the drug and even cause adverse reactions.Applications1. BiologicsFor biologic drugs (such as monoclonal antibodies or protein-based therapies), patients may develop anti-drug antibodies (ADA), which can neutralize the potency of the drug or accelerate its ...
Active pharmaceutical ingredients (APIs) are biologically active components in pharmaceutical drugs, responsible for the intended therapeutic effects. APIs are prepared through chemical synthesis or biotechnology, meeting stringent quality standards and regulatory requirements. ...
By leveraging deep insights into molecular structures, scientists can sculpt innovative drug candidates with unprecedented precision and finesse, ushering in a new era of personalized and targeted therapies. ...
Ongoing research and inventions in the field of oncology focus on the development of small molecule drug therapies for use in brain tumor resection. Small molecule drugs are being developed to target and effectively treat brain tumors to improve therapeutic outcomes. ...
They can usually be used to treat rheumatoid arthritis. These drugs are used to treat rheumatoid arthritis. Currently, researches on monoclonal antibody drugs development expand the range to immuno-oncology, targeted therapy, and immunotherapy. Researchers have proposed more prospects for monoclonal antibody therapy ...
It has been approved by the U.S. Food and Drug Administration It is certified by the Food and Drug Administration (FDA) and is a copolymer material available on the market. ...
The sleep apnea device market has undergone rapid transformation, driven by growing awareness about the consequences associated with disruptive or poor sleep conditions. Sleep apnea is a severe sleeping disorder in which a person experiences interruptive breathing or loud snoring. Long-term untreated or undiagnosed sleep apnea can cause several health problems, such as daytime sleepiness, ...
For instance, studying the enzymes involved in carbohydrate synthesis can help researchers develop new drugs and therapies for metabolic disorders, such as diabetes. By targeting specific enzymes, it may be possible to regulate carbohydrate metabolism and improve glucose homeostasis in individuals with diabetes. ...
The linker is not only the molecule part of the covalent link between the antibody and the small molecule payload, but also a key element with design properties in targeted drug therapy. The addition of the linker should not induce aggregation and needs to ensure acceptable PK characteristics, while limiting the premature release of the payload in plasma and ...
This could revolutionize the field of organ transplantation and offer hope to patients with organ failure. Drug testing: Bioprinted tissues can be used to test new drugs and therapies in a more realistic and humane way than traditional animal models. ...
ByMatexcel
Over the years, several innovative drug delivery systems have been developed to improve drug efficacy and patient outcomes. ...
In addition to traditional small molecule compounds, new types of payloads such as PROTACs and light-activated molecules have also been selected as payloads.New Strategies for ADC PayloadsADC with PROTAC Molecules as PayloadA major challenge in ADC development is dose-limiting toxicity (DLT), which demonstrates the difficulty in balancing the efficacy of drug ...
Factors Considered When Determining Shelf Life Expiration Dates Shelf life expiration dates are vitally important to ensure medical devices are safe to use. The Food and Drug Administration (FDA) requires product labels to indicate an expiration date if a certain component is not useful past a certain date. ...
What is CAR T-cell therapy? Car-t cell therapy involves genetically engineering T cells isolated from patients or allogeneic donors to express chimeric antigen receptors (CAR) that specifically recognize and kill tumor cells. As a "living" drug, CAR-T therapy is very different from traditional drugs. It is a ...
Echocardiographic imaging helps visualize hypertrophy, aiding in treatment planning and execution, enhancing patients' quality of life. 3. Emerging Therapies for Treatment of Heart Conditions In recent years, there has been a notable surge in the development and adoption of novel drug therapies aimed at addressing various cardiovascular ...
From exploring their roles in some neurological disorders, cardiovascular diseases to electrolyte imbalance—it's a resourceful tool. Research into new drug targets heavily relies on these systems. By manipulating these channels, researchers can evaluate the influence of potential drugs and analyze associated side effects. This increases the chance of ...