Endocrine Response Articles & Analysis
3 articles found
The US Environmental Protection Agency has responsibility for assessing endocrine activity of more than 10 000 chemicals, a task that cannot reasonably be achieved solely through use of available mammalian and nonmammalian in vivo screening assays. Hence, it has been proposed that chemicals be prioritized for in vivo testing using data from in vitro ...
Endocrine disrupting compounds (EDCs) can impact the reproductive system by interfering with the hypothalamic‐pituitary‐gonadal (HPG) axis. While in vitro testing methods have been developed to screen chemicals for endocrine disruption, extrapolation of in vitro response to in vivo action shows inconsistent accuracy. ...
The endocrine responses in male Murray rainbowfish (Melanotaenia fluviatilis) have been evaluated after exposures to biologically active concentrations of the non‐steroidal pharmaceutical, flutamide. ...