Enzyme Replacement Therapy Articles & Analysis
3 articles found
Notable examples include PEGylated interferons used in the treatment of hepatitis and PEGylated enzymes for enzyme replacement therapies. Reducing Immunogenicity Immunogenicity, the ability of a substance to provoke an immune response, is a significant concern in biopharmaceuticals. ...
Introduction MPS I is caused by a deficiency of the lysosomal enzyme a-L-iduronidase (IDUA) leading to GAG accumulation in multiple tissues and organs This accumulation results in a complex array of progressive, multi-systemic pathologies, including CNS manifestations Approved therapies include enzyme replacement ...
MPS I is caused by deficiency of the lysosomal enzyme a-L-iduronidase (IDUA) leading to GAG accumulation in multiple tissues and organs This accumulation results in a complex array of progressive, multi-systemic pathologies, including CNS manifestations Approved therapies include enzyme replacement therapy ...