Gene Regulatory Network Articles & Analysis
4 articles found
It comprehensively analyzes and identifies transcripts in cells or tissues through high-throughput sequencing technology, and quantitatively and functionally analyzes them through bioinformatics methods to reveal gene expression regulatory networks and related biological functions. ...
Although peroxisome proliferator-activated receptor alpha (PPARa) signaling is most active in cardiac myocytes, these authors noted that PPARd signaling plays a separate and important role in effectively activating gene regulatory networks, increasing the number and distribution of organelles involved in energy production, and enhancing fatty ...
For example, incorporating RNA-seq DE analysis with quantitative PCR (qPCR) and transcription factor binding site information allowed researchers to identify gene regulatory networks underlying the development of alternative jaw phenotypes in cichlid fish. Measurement of gene expression in wild populations and natural settings ...
Fish were sampled at three time points and examined for developmental and skeletal morphology, apical thyroid and skeletal gene markers, and modifications in swimming behavior (as adults). Exposure to the high mixture resulted in > 85% mortality within one week of exposure, despite being below reported acute toxicity thresholds for individual congeners. ...