Genomic Location Articles & Analysis
2 articles found
In the realm of genetic engineering and genome editing, single guide RNA (sgRNA) plays a pivotal role, particularly in the context of CRISPR-Cas9 technology. The effectiveness of CRISPR-Cas9 hinges largely on the design and confirmation of sgRNAs, which direct the Cas9 protein to specific genomic locations. This article delves into the key ...
Methodologies for Creating Custom Knockout Cell Lines CRISPR-Cas9 Technology: CRISPR-Cas9 has revolutionized genome editing due to its simplicity and efficiency. Researchers design guide RNA (gRNA) that directs the Cas9 nuclease to a specific genomic location. Once the target gene is located, Cas9 induces a double-strand break, ...