- Home
- Articles
- latamerica
- genomic profiling
Genomic Profiling Articles & Analysis
17 articles found
Abnormalities in the genome can lead to tumorigenicity or other adverse effects, making regular genomic assessment a vital part of iPSC characterization. Epigenetic Profiling The epigenetic landscape of iPSCs also plays a significant role in their characterization. ...
Clinical trials are the backbone of modern medicine, responsible for bringing innovative, safe, and efficient treatments to market after rigorous testing and evaluation. However, the conventional process of conducting these trials has often been long, expensive, and fraught with inefficiencies¹. The advent of predictive analytics is reshaping the landscape of clinical trials, ushering in a ...
Medical advancement relies on clinical trials, which are essential for the development of safe and effective innovative treatments. However, the success and general applicability of these treatments heavily depend on the diversity of the participants involved¹?³. This blog explores the importance of achieving data diversity in clinical trials to enhance clinical trial results and ...
Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...
In response to the emerging needs in global healthcare, SOPHiA GENETICS has just revealed the New Generation SOPHiA DDM™ Platform, aiming to stay at the forefront of precision medicine and address today the healthcare needs of tomorrow. ...
CD Genomics, a well-established leader in transcriptome solutions, is pleased to announce the introduction of Ribosome Profiling technology. ...
sgRNA based genetic screens provide a robust platform for functional genomics, promoting research in fields such as oncology, immunology, and molecular biology. ...
Small RNA sequencing, an example of targeted sequencing, is a powerful method for small RNA species profiling and functional genomic analysis. Here, we present the guidelines for bioinformatics analysis of small RNA sequencing. ...
Introduction Since the completion of the Human Genome Project, genomics has played an increasingly critical role in the biomedical field. ...
Personalised medicine promises to transform healthcare with treatments tailored to a patient’s unique genetic profile (genomics) and by leveraging their genomic data to predict drug targets that will improve treatment outcomes (pharmacogenomics). ...
ByLifebit
Denget al. report on a technique called spatial-CUT&Tag for genome-wide profiling of histone modifications pixel by pixel on a frozen tissue section without dissociation. ...
Many analyses, such as differential gene expression analysis, immunological gene signature analysis, gene pathway analysis, T/B-cell receptor inference, HLA inference, and viral transcript quantification, can be performed on the data after it has been sequenced. DNA-Seq in Cancer Research Genomic testing can discover or profile the somatic or acquired ...
Establishing phylogenetic relationships can also help in comprehending the behavior of microbial groups and predict their evolutionary tendencies. 16S, 18S, and ITS amplicon sequencing provide a rapid and accurate method of microbial classification that can be useful for microbial profiling studies. About CD Genomics CD Genomics has become ...
Over time, genetic research have recognized a number of genetic danger variants related to neurodegenerative problems and helped reveal new organic pathways and genes of curiosity. Nevertheless, genetic danger variants generally reside in non-coding areas and should regulate distant genes reasonably than the closest gene, in addition to a gene’s interplay companions in organic networks. ...
Similarly, population level data for immunity profiles of specific patient groups could be used to reduce the amount of data required to make inferences for individual patients. ...
In order to dissect the initiation of early organogenesis at the whole embryo scale, it is desirable to not only measure genome-wide molecular profiles for cell type identification but also interrogate spatial organization in the tissue context with high spatial resolution. ...
"We have shown that the IL-2-triggered immunomodulatory capacity of MSCs could be severely affected by replicative aging," notes Ping Niu, MD, PhD, an associate chief physician at Wuhan University and the first author on the paper. In fact, genome-wide transcriptional profiling of MSCs from human patients exposed to therapeutic doses of IL-2 showed significant ...