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Harvesting System Articles & Analysis
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While upstream cell culture or fermentation focuses on producing the target biomolecule, downstream steps transform crude harvests into highly purified and stable therapeutic products. For biologics such as monoclonal antibodies, recombinant proteins, and viral vectors, downstream processing can account for the majority of production costs, making process optimization both a ...
Introduction The BALB/C mouse is a widely used inbred strain in biomedical research, particularly in the fields of immunology, cancer research, and genetics. Among the various tissues studied, the kidney holds significant importance due to its complex structure and multifaceted role in physiological functions. A formalin-fixed paraffin-embedded (FFPE) block of the BALB/C mouse kidney serves as an ...
This method is particularly appealing for large-scale production, as biological systems can often yield high quantities of specific lipids with natural stereochemistry. ...
Adenoviruses are a group of viruses that have gained significant attention in recent years, particularly in the fields of gene therapy, vaccine development, and cancer treatment. With their ability to deliver genetic material into cells effectively, adenoviruses serve as valuable vectors in various biomedical applications. To harness their potential, specialized adenovirus production services ...
Advantages of Lentivirus as a Delivery System Lentiviruses, a subclass of retroviruses, play a crucial role in the delivery of CRISPR/Cas9 components. ...
The C57BL/6 mouse strain, commonly referred to as C57, has become a standard in biomedical research due to its well-documented genetic background and immune system. This strain’s response to various stimuli, including allergens, pathogens, and other environmental factors, makes it particularly valuable for studying lung diseases and conditions, such as asthma and pulmonary ...
Human mesenchymal stem cells (hMSCs) are a remarkable type of stem cell found in various tissues, such as bone marrow, adipose tissue, and umbilical cord. These cells have garnered significant attention in the field of regenerative medicine and therapeutic research due to their unique properties and potential applications. Characteristics of hMSCs hMSCs possess the ability to differentiate into ...
However, if parents consent, the cord can be harvested for its valuable cells. This process is ethical and poses no risk to the mother or infant, thus making Wharton’s jelly a readily available source of stem cells. ...
The cosmetics and skincare industry is constantly evolving and a recent trend that has emerged is the use of fermented ingredients in skincare products. Fermentation is a microbial metabolic process that has been used for centuries in food and beverage production, and now it has been extended to the cosmetic industry.What are Fermented Raw Materials?Fermented raw materials are natural ingredients ...
Native Porcine Pancreatin, an enzymatic mixture derived from the porcine pancreas, has emerged as a fundamental component in various industries due to its unique enzymatic composition. Comprising amylase, lipase, and protease enzymes, this preparation is celebrated for its multifaceted applications and plays an indispensable role in the pharmaceutical, food, and biotechnology sectors. In this ...
The advantage of the in-solute capturing method is that the use of magnetic beads allows the reaction to be more effective by shaking or heating the system. Both of the methods are effective ways to extract the exome from the genome. ...
Explore how surgeons are using COREX to harvest cancellous bone graft using a minimally invasive ...
The study of the metatranscriptome through Next-Generation Sequencing techniques allows us to obtain gene expression profiles from whole microscopical populations, providing new insights into poorly known biological systems and overcoming technical limitations related to individual bacteria isolation. Challenges of metatranscriptomic sequencing Although current ...
Very rarely does a high school student who aspires to study medicine get a first-hand opportunity to be a medical trailblazer. But 15-year-old Luna Martini stepped comfortably into that role when she became the first patient in Connecticut to receive a BEAR® Implant to treat her torn anterior cruciate ligament (ACL). A freshman at Farmington High School, Luna aspires to be a doctor herself ...
Before any new medical technology is approved for use by the U.S. Food and Drug Administration, a considerable number of courageous patients must first agree to participate in clinical trials of the new technology – without any data on potential success rates. For the BEAR® Implant, that brave patient was Corey Peak, a recreational athlete who tore his anterior cruciate ligament (ACL) ...
The recipient area is prepared by an appropriate size of Osteoarticular Transfer System trephine (10 mm), which is introduced to a depth of 15 mm, in this patient while the ankle was in plantar flexion (Fig 4). Then, the wound is closed with a salinedampened sponge and the iliac crest is prepared for graft harvest. After a mini-incision on skin and subcutaneous ...
As one of the primary biomolecules in nature, carbohydrates are critical elements in nutrition provision, energy transportation, cell composition, etc. In view of their universality and essentiality in research, this article is an exploration of carbohydrates, especially those hot ones in the market. Chemical Classifications of Carbohydrates There are different ways to classify carbohydrates, ...
The biopsy needle was drilled through the bone for tissue harvesting using the Teleflex Arrow OnControl system, also under live imaging. ...
Autologous vein is preferable but requires time to harvest and may not be available. Synthetic grafts are poorly resistant to infection and associated with thrombotic complications. ...
Abstract Objective: Vascular conduit is essential for arterial reconstruction for a number of conditions, including trauma and atherosclerotic occlusive disease. We have developed a tissue-engineered human acellular vessel (HAV) that can be manufactured, stored on site at hospitals, and be immediately available for arterial vascular reconstruction. Although the HAV is acellular when implanted, ...