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Hemodynamic Articles & Analysis
11 articles found
The evaluation of cardiovascular toxicity is a significant challenge in drug development. Preclinical evaluation of cardiovascular safety involves a multifaceted approach, encompassing a plethora of in vitro and in vivo endpoints. These assessments continuously evolve, aiming to mitigate the incidence of cardiovascular toxicity that may emerge during clinical trials. To shed light on the ...
Preliminary results of a large-scale study demonstrating the clinical benefits of EchoGo® Heart Failure were shared at the American College of Cardiology (ACC 2023) conference last month. Using only an apical four-chamber ultrasound view, this new AI-enabled platform can identify heart failure with preserved ejection fraction (HFpEF) and has been shown to minimize the indeterminate ...
Heart failure with preserved ejection fraction (HFpEF) has recently been recognized as the single greatest unmet need in cardiovascular medicine, overtaking heart failure with reduced ejection fraction (HFrEF) and becoming the most common form of heart failure, with a prevalence that is increasing by 1% annually.[1] Despite this, there remains no gold standard in diagnosing HFpEF. Diagnosing ...
The combination of congenital heart disease (CHD) and respiratory distress syndrome (RDS) can present a difficult scenario to manage with conventional mechanical ventilation (CMV). Our patient presented with poor right ventricular (RV) function, and refractory respiratory failure on CMV. High-frequency jet ventilation (HFJV) was used in order to improve ventilation at a similar or lower mean ...
Abstract : Intimal hyperplasia is one of the prominent failure mechanisms for arteriovenous fistulas and arteriovenous access grafts. Human tissue-engineered vascular grafts (TEVGs) were implanted as arteriovenous grafts in a novel baboon model. Ultrasound was used to monitor flow rates and vascular diameters throughout the study. Intimal hyperplasia in the outflow vein of TEVGs was assessed at ...
MAP and HR was maintained within normal threshold throughout most of the case. The patient had a SVR >1200 dynes for more than 88% of the case indicating physiological or drug-induced vasoconstriction. Argos provided data that consistently showed the subtle changes in hemodynamics helping to inform decisions for a more targeted ...
Protamine is a standard therapy during CABG surgery and hemodynamic responses (i.e., small decreases in systemic blood pressure) to protamine are common. Argos followed a change in HR from 90 to 70, which coincided with an increase in SVR following protamine administration. To maintain a low MAP per the surgeon's request, Argos shows a trend of decreasing SVR coincident with a decreasing MAP, ...
Background Esophagectomy for cancer involves two- or three-phase procedures, such as abdominal, chest and/or neck incisions, is more invasive than other types of gastrointestinal surgery, and is associated with high risk for postoperative morbidity. Because of this risk, perioperative management of circulatory conditions such as hypovolemic hypotension is especially important to avoid ...
In-vivo Evaluation Of A Novel Surgical Heart Valve Prosthesis Designed To Be Durable, Anticoagulant-free And Silent. Bart Meuris, Lucas Van Hoof, Wilm Decré, Marie Lamberigts, Tom Langenaeken, Peter Verbrugghe. KU Leuven, Leuven, Belgium. OBJECTIVE: Heart valves prostheses still face limitations: reoperations with tissue valves or lifelong anticoagulation with mechanical valves. The ...
The need for providing dialysis to patients in the ICU has increased overtime. Delivery of this care is challenging to health care systems (HCS) both in costs and ...
Background: Uncontrolled hemorrhage remains one of the most challenging problems facing emergency medical professionals and a leading cause of traumatic death in both battlefield and civilian environments. Survival is determined by the ability to rapidly control hemorrhage. Several commercially available topical adjunct agents have been shown to be effective in controlling hemorrhage, and ...