Hepatic Enzyme Articles & Analysis
2 articles found
Notable examples include PEGylated interferons used in the treatment of hepatitis and PEGylated enzymes for enzyme replacement therapies. Reducing Immunogenicity Immunogenicity, the ability of a substance to provoke an immune response, is a significant concern in biopharmaceuticals. ...
This study assessed the effects of 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD), 2,3,4,7,8‐pentachlorodibenzofuran (PeCDF), and 2,3,7,8 tetrachlorodibenzofuran (TCDF) on the incidence of jaw lesions and on hepatic cytochrome P4501A (CYP1A) endpoints in mink (Mustela vison). Adult female mink were assigned randomly to one of 13 dietary treatments (control and four increasing doses ...