Hepatic Expression Articles & Analysis
6 articles found
Here we show that SRSF3 is decreased in human liver samples with nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), or cirrhosis that was associated with alterations in RNA splicing of known SRSF3 target genes. Hepatic SRSF3 expression was similarly decreased and RNA splicing dysregulated in mouse models of NAFLD and NASH. ...
In the present study, BPS was injected into the air cell of unincubated, fertilized chicken embryos at 6 concentrations ranging from 0 to 207 µg/g egg to determine effects on pipping success, development, hepatic mRNA expression, thyroid hormone levels, and circulating bile acid concentrations. ...
Here, we examine the endocrine and physiological effects of short‐term, acute exposure of environmentally relevant concentrations of analytical grade atrazine in juvenile barramundi (Lates calcarifer) in a controlled laboratory experiment. Expression of hepatic vtg was not affected supporting previous studies that atrazine does not have a direct estrogenic effect ...
Zebrafish (Danio rerio) embryos (F0) were exposed to low concentrations (3, 10, 30 μg/L) of the PBDE mixture DE‐71 until they were sexually mature, and steroid hormone production, expression of genes involved in steroidogenesis, gonadal development and gamete characteristics were examined. ...
Fish were exposed to nominal concentrations of 125, 250, 500 and 1000 µg/L of flutamide for 7 days, after which plasma vitellogenin concentration, brain aromatase activity and hepatic expression of the genes for vitellogenin, choriogenin and androgen and estrogen receptors were assessed. ...
This study assessed the effects of 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD), 2,3,4,7,8‐pentachlorodibenzofuran (PeCDF), and 2,3,7,8 tetrachlorodibenzofuran (TCDF) on the incidence of jaw lesions and on hepatic cytochrome P4501A (CYP1A) endpoints in mink (Mustela vison). Adult female mink were assigned randomly to one of 13 dietary treatments (control and four increasing doses of TCDD, PeCDF, or ...