Hepatic Lipid Articles & Analysis
3 articles found
Meanwhile, as an important signaling molecule, bile acids can activate the relevant receptors to maintain the homeostasis of hepatic glucose and lipid metabolism, and interact with gut bacteria to regulate the development of the intestine and the inflammatory response of the body. ...
Introduction Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic manifestations of metabolic disorders, ranging from simple steatosis to nonalcoholic steatohepatitis (NASH), an aggressive histological form, ultimately leading to advanced fibrosis and cirrhosis. ...
Previously, we demonstrated that SRSF3 regulates splicing of the insulin receptor gene (INSR) (8) and plays an important role in hepatocyte differentiation and hepatic glucose and lipid metabolism (9). Furthermore, we have shown that hepatocyte-specific deletion of the SRSF3 gene (SRSF3H-KO) promotes hepatocellular carcinoma (HCC) in aged SRSF3H-KO mice (10, 11), ...