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Human Chemokine Articles & Analysis

1 articles found

Based on Antibody Targeted Protein Degradation

Based on Antibody Targeted Protein Degradation

To validate the KineTAC platform design concept, the authors developed KineTAC bispecific antibodies targeting different target proteins (PD-L1, HER2, PD-1, EGFR, CDCP1, and TROP2). The N-terminus of the human CXCL12 chemokine was fused to the Fc domain of the bispecific antibody to form the cytokine-binding arm, and the antigen-binding arm contained ...

ByBOC Sciences

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