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Human Clinical Trial Articles & Analysis
18 articles found
Animal models play a critical role in biomedical research, as they allow scientists to study complex disease processes, develop new therapies, and test their safety and efficacy before moving into human clinical trials. To date, several excellent models have already been developed, such as the GAA-knockout mouse model for Pompe’s disease ...
They help bridge the gap between in vitro studies and clinical trials, allowing researchers to gain a better understanding of how a drug behaves in a living organism. ...
Check out clinicaltrials.gov, which is a registry of clinical trials that provides the public with information on past and current trials. ...
The World Health Organization in its report on Neglected Tropical Diseases has stated that there is overwhelming evidence to show that the burden caused by many of the 17 diseases that affect more than 1 billion people worldwide can be effectively controlled and, in many cases, eliminated or even eradicated. Leishmaniasis caused by Leishmania spp is one such example and poses a grave health risk ...
Schistosomiasis is a major neglected tropical disease (NTD) of public health concern to a billion people. Currently an estimated 200 million are infected and an additional an estimated 800 million people are at risk of acquiring this disease in 74 countries. The disease carries high morbidity. Revised estimates of disability adjusted life years (DALYs) and recent calculations based on ...
SmartTab is pioneering a wireless remote controlled drug delivery system, has completed pre-clinical animal studies and is preparing for human clinical trials for its core technology TargetTab™. ...
BySmartTab
These henipaviruses span species and can infect many other mammals including humans. These viruses cause brain inflammation and respiratory symptoms. ...
The researchers said they'll keep testing this transitory mRNA-based CAR-T cell therapy and expect to move forward to human clinical trials as soon as possible. ...
Innovations and Iterations In the consumer tech world, iterations happen very fast, though most inventions are not ‘one and done’ masterpieces: the Dyson cyclone vacuum cleaner made 5,127 prototypes. In the medical device world, development takes longer because of the appropriate and necessary regulations and need for safety. Using an agile approach, but with safety and reliability ...
However, these studies can be lengthy and expensive and may not accurately recapitulate the behavior of the human gastrointestinal tract. Drugs are thus often developed with undesired gut side effects that are not apparent until clinical trials. ...
Myles Greenberg describes this exciting new technology and the path to patients, with first-in-human clinical trials launching earlier this year. What is the story behind the technology? ...
Bharat Biotech in Hyderabad, India will then begin production scale-up for safety and efficacy testing in humans. CoroFlu could be in human clinical trials by the fall of 2020. Four Phase I and Phase II clinical trials involving hundreds of subjects have shown the M2SR flu vaccine to be safe and ...
The enzyme-linked immunosorbent spot (ELISpot) assay is one of the most commonly used methods to measure antigen-specific T cells in both mice and humans. Some of the primary reasons for the popularity of the method are that ELISpot is highly quantitative, can measure a broad range of magnitudes of response and is capable of assessing critical cellular immune-related activities ...
So far, according to Kunicher, the team has completed animal trials. Human clinical trials are slated to launch within the next 12 months. Animal trials don’t always translate to humans because of species differences, among other reasons. ...
“I think one of the things that makes 2019 interesting for us is that it’s going to be the first time physicians and the market and our competitors and patients get to see the new devices and [we will] treat our first patients,” said the co-founder, of the first human clinical trials. 2019 also is the first opportunity for ...
If IDCT demonstrates similar results in humans, the outcome could be reduced pain and disability, potentially eliminating the need for opioid usage as a pain reliever from the get-go. ...
This purified vaccine was tested in the clinical phase I/II trial in healthy non-infected adults in China. About 518 volunteers in Southern region and 650 volunteers from the Northern region of China were vaccinated. ...
Xenotransplantation (XTP) involves the transplantation of cells, tissues and organs from non-human mammals (usually pigs) to humans. Because XTP could produce considerable public health gains, advocates want to proceed to human clinical trials as soon as possible. ...