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Human Gastrointestinal Articles & Analysis

2 articles found

Increasing the Efficiency of Drug Development with Preclinical Testing Using Human Intestinal Stem Cells

Increasing the Efficiency of Drug Development with Preclinical Testing Using Human Intestinal Stem Cells

However, these studies can be lengthy and expensive and may not accurately recapitulate the behavior of the human gastrointestinal tract. Drugs are thus often developed with undesired gut side effects that are not apparent until clinical trials. ...

ByAltis Biosystems


Defining cell culture conditions to improve human norovirus infectivity assays

Defining cell culture conditions to improve human norovirus infectivity assays

Significant difficulties remain for determining whether human noroviruses (hNoV) recovered from water, food, and environmental samples are infectious. Three-dimensional (3-D) tissue culture of human intestinal cells has shown promise in developing an infectivity assay, but reproducibility, even within a single laboratory, remains problematic. From the ...

ByIWA Publishing

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