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Immune Antibody Articles & Analysis
22 articles found
At present, recombinant protein drugs are widely used in various fields such as tumors, autoimmune diseases, metabolic diseases, geriatric diseases, and degenerative diseases.FcyR (Fc gamma receptors) are receptors expressed on the surface of immune cells, primarily responsible for recognizing and binding to the Fc (Fragment crystallizable region) part of ...
Immunomodulatory Therapies The concept of harnessing the body’s immune response against viral infections has gained traction over the years. Immunomodulatory therapies aim to enhance the immune system’s ability to recognize and eliminate viral pathogens. In 2024, the development of monoclonal antibodies and immune ...
Proteins, such as lectins or glycan-binding antibodies, often recognize specific sugar motifs, and understanding these interactions is critical for deciphering their roles in biological processes like cell signaling, immune response, and pathogen recognition. ...
Antibody EngineeringAntibody sequencing can provide information for optimizing antibody design, such as changing the antibody's affinity, specificity or half-life in the body.2. Analysis of Immune ResponseSequencing can be used to study the role of the Boxcab ab antibody in the immune response, ...
The antibody sequence can be used to create vaccines, develop new treatment strategies, and even analyze the functioning of the immune system. ...
Through this method, we can clarify the relationship between the sequence and the cell, thus discovering antibodies with special properties. These antibodies may have high affinity for targets, can effectively counteract pathogens, or participate in the body's own immune response.2. ...
Drug antibody testing is a laboratory testing method specifically designed to evaluate the immune response of the human body to certain drugs. ...
There are unlimited uses for point mutation cell lines at pre-defined loci, including functional assays, drug screening, FACS screening of membrane proteins, gene expression studies, gene therapy and antibody immunization boosting research. The RNA-guided DNA endonuclease Cas9 associates with a synthetic single guide RNA (gRNA) and cleaves double-stranded DNA ...
Yeast produces biotinylated recombinant antibodies in vivo. Researchers have now developed a new method to generate in vivo biotinylated recombinant antibodies secreted by yeast. ...
Fc-Fusion Glycosylation and Its Biological Significance Glycosylation Therapeutic monoclonal antibodies (mAb) or mAb variant molecules such as Fc-Fusion have an N-linked glycan coherent sequence of (Asn)-X-Ser/Thr (where X is any amino acid except Pro) at the Asn297 position of the heavy chain of the constant CH2 domain, and some mAb also have additional glycosylation ...
The discovery of antibody drugs is a rapidly developing field, and antibody modeling services offer reliable and efficient tools for their discovery and design. By predicting the interactions between antibody drugs and molecular targets, antibody modeling services can enhance the affinity and specificity of ...
IL-17C therefore serves as an epithelial stimulant of immune response, operating independently of T cells [3]. IL-17E (IL-25) IL-17E induces keratinocyte proliferation and can activate innate immune cells. ...
Why target GPCRs with antibodies? The G Protein-coupled receptor (GPCR) superfamily represents the largest and single most important family of human drug targets. ...
Background Tumor immunotherapies compose immune checkpoint inhibitors, therapeutic antibodies, tumor vaccines, cellular therapies, and so on. ...
The analysis indicates which region of the viral receptor-binding protein is dominant in eliciting immune responses. Before this study, there was no data on the structure of the HNV G protein, a key part of the antibody response elicited by henipaviruses, the researchers said. ...
While the existing intramuscular vaccines on the market today generally have only humoral and cellular immunity, the vaccine given in the arm produces antibodies in the blood, but few antibodies reach our nasopharyngeal mucosa, which, together with the gradual decline in the level of neutralizing antibodies in the body after ...
The interesting SARS-CoV-2 omicron mutant strain evades immunity mediated by antibodies from vaccination or infection with early mutants due to the accumulation of a large number of spike mutations. Recently, in a research report titled "Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement" published in Science, ...
However, there is uncertainty about the duration of immunity, evolution of IgG antibody levels and IgG avidity (an index of antibody-antigen binding strength), and differences in the immune responses between vaccines. ...
The study of both serum antibodies and antibodies encoded by memory B cells in donors with recent AAV exposures can reveal key characteristics of human anti-capsid antibody responses and provide a more complete picture of anti-capsid antibody immunity. ...
Every year, millions of people are vaccinated to strengthen their immunity and protect themselves from infectious diseases. According to the regulations of the World Health Organization (WHO), vaccination is an approved tool for dealing with deadly contagious diseases that kill 3 million people worldwide. ...
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