Immune Co Stimulation Articles & Analysis
13 articles found
The field of immunology has experienced significant advancements over recent years, particularly in the area of recombinant vaccine production. This innovative approach has revolutionized the way vaccines are developed, manufactured, and administered, offering a promising alternative to traditional methods. By utilizing recombinant DNA technology, scientists can produce vaccines that are more ...
In recent years, mRNA vaccines have emerged as a revolutionary tool in the fight against infectious diseases, including the ongoing COVID-19 pandemic. These vaccines utilize messenger RNA (mRNA) to instruct cells to produce a protein that triggers an immune response, leading to the production of antibodies that protect against the targeted virus. While mRNA vaccines have shown remarkable efficacy ...
Poly(lactic-co-glycolic acid) (PLGA) is a functional polymer organic compound randomly polymerized by lactic acid (PLA) and glycolic acid (PGA). ...
Cytokines are a broad class of tiny proteins that are essential for controlling inflammation and immunological responses. Numerous cell types, including fibroblasts, endothelial cells, immunological cells, and epithelial cells, produce these signaling molecules. Serving as intermediaries, they synchronize various cell functions to elicit the body's defense mechanisms against infections, tissue ...
Infectious diseases seriously threaten human health, and various infectious diseases may cause millions of severe cases and even death every year. Vaccination has been one of the most effective public health interventions in history, preventing millions of deaths worldwide. However, the success of vaccines relies not only on the antigens they carry but also on additional components known as ...
A new study by scientists at Scripps Research shows that the anxiety that develops during abstinence from excessive drinking can lead to relapse, and that anxiety may be caused in part by the release of immune proteins in the brain. The findings, published online recently in Molecular Psychiatry, shed light on the molecular details of the brain's response to alcohol addicts and ...
Cytokines are a class of small molecule proteins secreted by cells that mediate and regulate immune processes, and they act in an autocrine, paracrine and endocrine manner. More than 200 types of human cytokines have been identified, which can be generally classified into interleukins, interferons, tumor necrosis factors, colony-stimulating factors, chemokines, growth factors, etc. according to ...
Researchers at the Children's Hospital of Philadelphia (CHOP) have made a breakthrough in the treatment of aggressive solid cancers, and they have developed a new cancer treatment that targets proteins within tumor cells that are essential for tumor growth and survival, but this has not been possible before. Using the power of large data and advanced computational methods, researchers can ...
Product name NKG2A and CD94 heterodimer (KLRC1), recombinant protein Full Product Name Recombinant human NKG2A and CD94 heterodimeric protein (N-8His and N-DYKDDDDK) Product synonym names Heterodimer NKG2A and CD94; Heterodimer KLRC1 and CD94; CD159A and KLRD1 heterodimer Product gene name Recombinant protein KLRC1 3D structure ModBase 3D Structure for P26715 Host: Human cells Purity ...
It is certain that RNA therapy is no longer a no-man's land for medical innovation. Not only have several products been launched and received good market response, but there are also many pipelines in the research and development side to advance to the middle and late clinical stage, and behind the boom are the technological breakthroughs of scientists. There are three key points in the ...
Researchers have delved further into our understanding of coronavirus, while the race to develop a vaccine continues. New advances in coronavirus understanding New research has put paid to some of the conspiracy theories surrounding coronavirus. A team comprising researchers from both the US, Australia and the UK has analyzed the receptor-binding domain (RBD) and the cleavage site present on ...
Many of the heparin dependent antibodies, including those with the IgG isotype, are asymptomatic, and only a subgroup of antibodies is positive in platelet activation assays. What differentiates pathogenic from asymptomatic antibodies is not fully understood, with the exception that there is some relationship between antibody concentration and occurrence of HIT, and that antibodies with the ...
Single and fractionated Whole-Body Irradiation (WBI) of the BALB/c mice with total doses of 0.1 or 0.2 Gy X-rays led to reductions in the number of pulmonary tumour colonies. Single and fractionated WBI with 0.1 or 0.2 Gy, as well as the fractionated exposure to 1.0 Gy X-rays, significantly stimulated: the cytotoxicity of macrophages (Mφ) and Natural Killer (NK) cells mediated mainly by ...