Immune Profiling Articles & Analysis
8 articles found
Overall, the integration of multi-omics data and advancements in immune-oncology plays a significant part in developing precise treatments for brain tumors2. Key techniques include multi-omics profiling, immune checkpoint blockers (ICBs), RNA-sequencing (RNA-Seq), single-cell analysis, imaging mass cytometry (IMC), and multiplexed ion beam ...
Cancer is a complex disease that involves a delicate interplay between the tumor cells and the host immune system. Cytokines play a critical role in this interplay, mediating the communication between different cells of the immune system and modulating immune responses. ...
Cancer is a complex disease that involves a delicate interplay between the tumor cells and the host immune system. Cytokines play a critical role in this interplay, mediating the communication between different cells of the immune system and modulating immune responses. ...
COVID-19 shares similarities with other respiratory infections, yet we still have a limited understanding of the immune response to SARS-CoV-2. To better understand the immune landscape of patients with severe COVID-19, a study led by Drs. Vick, Frutoso, Prlic, and Lund characterized the immune profile of hospitalized COVID-19 ...
The study of the metatranscriptome through Next-Generation Sequencing techniques allows us to obtain gene expression profiles from whole microscopical populations, providing new insights into poorly known biological systems and overcoming technical limitations related to individual bacteria isolation. ...
Bacteriocins are small, thermostable, ribosomally synthesized antimicrobial peptides produced by bacteria that are active against other bacteria and to which the producer is immune. They exhibit considerable diversity in size, structure, mechanism of action, inhibitory profile, immune mechanism, and target cell receptors. ...
However, they tend to trigger strong immune responses in humans, which limits their applicability for gene therapy applications, particularly in immunocompromised patients [1]. Compared to adenovirus and lentivirus, AAV offers a low immune profile, relative safety, long-lasting expression in non-dividing cells, and a long scientific and clinical ...
The challenges of evading both pre-existing immunity and de novo adaptive immune responses against AAV vectors are made especially difficult by the heterogeneous nature of patient immune responses and immune histories. ...