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Immune Regulatory Articles & Analysis

6 articles found

Significance of Host Cell Protein Residue Detection in Biopharma

Significance of Host Cell Protein Residue Detection in Biopharma

|Certain host proteins may induce an immune response.|Regulatory agencies have strict standards that require the amount of host protein residue in biological products to be within a safe range.Host protein residue detection is a critical step in the biopharmaceutical process to ensure product quality and safety. ...

ByMtoZ Biolabs


Differentiation and Functions of Th17/Treg Cytokines

Differentiation and Functions of Th17/Treg Cytokines

T cells are the most numerous and functionally complex type of lymphocytes, mainly including CD4+ T cells and CD8+ T2 cells, which play an important role in cellular immunity and assist in humoral immune response. According to their functions in the immune response, T lymphocytes mainly include helper T cells (Th cells), ...

ByCreative Proteomics


Cytokines: Characteristics, Applications, and Quantitative Analysis

Cytokines: Characteristics, Applications, and Quantitative Analysis

These molecules are synthesized and secreted primarily by immune cells (including monocytes, macrophages, T cells, B cells, and NK cells) as well as certain non-immune cells (such as endothelial cells, epidermal cells, and fibroblasts) upon specific stimulation. Cytokines play pivotal roles in regulating intrinsic and adaptive immunity, ...

ByCreative Proteomics


IL-2 and IL-2 Receptor Series: Pioneering Solutions for Immunotherapy Research

IL-2 and IL-2 Receptor Series: Pioneering Solutions for Immunotherapy Research

In addition, it aids in the development of regulatory T cells (Tregs), thereby producing peripheral T cell immune tolerance, as well as regulating the proliferation and differentiation of activated T cells. ...

ByBeta Lifescience


Punctuating messages encoded in human genome with transposable elements

Punctuating messages encoded in human genome with transposable elements

Jordan's team, allowed them to pinpoint the location of thousands of individual MIR elements in the human genome that appear to function as so-called "boundary elements" in T lymphocyte cells of the immune system. Boundary elements are epigenetic regulatory sequences that separate transcriptionally active regions of the human genome from transcriptionally silent ...

ByAelan Cell Technologies


Synthesis of high aspect ratio gold nanorods and their effects on human antigen presenting dendritic cells

Synthesis of high aspect ratio gold nanorods and their effects on human antigen presenting dendritic cells

Low AR (~4.5) gold NRs induced considerable cell death due to CTAB, while spherical gold NPs (7 nm) and high AR (~21) gold NRs showed no or minor effects on viability and immune regulatory markers, which supports the further development of high AR gold NRs for medical applications.Keywords: gold nanorods, non-seeded, nitric acid, high aspect ratio, ...

ByInderscience Publishers

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