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In Vivo Calcium Imaging Articles & Analysis
4 articles found
Click chemistry has revolutionized the field of bioconjugation, offering a robust and versatile approach for linking biomolecules, such as proteins, peptides, nucleic acids, and carbohydrates, to create novel materials and probes. Traditionally, copper-catalyzed azide-alkyne cycloaddition (CuAAC) has been the cornerstone of click chemistry, but concerns about cytotoxicity and metal contamination ...
Introduction For years, scientists have leveraged the brilliant potentialities of genetic science to explore how cells function and interact in living organisms. Among the numerous tools employed are "reporter systems," which use a visible marker to track gene expression, protein interactions, and other vital biological processes. One such system employs reporter lentiviral particles, using the ...
Due to the high sensitivity, flexibility, selectivity, and environmental stability, fluorescent techniques are broadly applied in biological research. Peptides provide unique possibilities for the development of efficient and selective fluorescent sensors because of their modular nature, synthetic accessibility, and biomolecular recognition potential. Accordingly, labeling peptides with ...
Quantum dots have the potential to be used as contrast agents for molecular imaging in vivo, but there are many challenges in optimising such procedures, both in pre-clinical animal models and in the potential clinical applications. In particular, it is critical to obtain the optimal target-to-background contrast to achieve maximum diagnostic accuracy. However, available data are insufficient to ...