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In Vivo Experimentation Articles & Analysis

7 articles found

Research Progress of Tetrahydrocurcumin

Research Progress of Tetrahydrocurcumin

Tetrahydrocurcumin (THC), as the most active and main metabolite produced in the metabolism of curcumin in vivo, can be isolated from the cytoplasm of the small intestine and liver after curcumin administration in human or mouse. ...

ByHunan Huateng Pharmaceutical Co. Ltd.


In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

The platform enables high-throughput computational compound screening based on experimentally validated simulations of in vivo pharmacokinetic-pharmacodynamic (PK-PD) phenomena. ...

ByVeriSIM Life


Accurately Recapitulating Environmental Niches in  Vitro Models of the Intestine

Accurately Recapitulating Environmental Niches in Vitro Models of the Intestine

While animal models possess system complexity, it is frequently difficult to modulate and control the desired experimental parameters in in vivo studies. Additionally, the intestinal systems and diets of most animals differ dramatically from those of humans. ...

ByAltis Biosystems


Administration of Lactobacillus fermentum KBL375 Causes Taxonomic and Functional Changes in Gut Microbiota Leading to Improvement of Atopic Dermatitis

Administration of Lactobacillus fermentum KBL375 Causes Taxonomic and Functional Changes in Gut Microbiota Leading to Improvement of Atopic Dermatitis

After cultivation, bacterial cells were harvested using centrifugation (1,200 × g) and washed twice with 1 × phosphate-buffered saline (PBS) prior to administration to mice. AD-Induced in vivo Mouse Model All experimental procedures for the AD-induced in vivo mouse model were approved by the Institutional Animal Care and Use ...

ByKoBioLabs


The Five Factors of Smart Laboratory Success

The Five Factors of Smart Laboratory Success

An innovative information platform to capture, integrate, manage and analyse in vivo experimental data in a much more coherent fashion was commissioned and deployed. ...

ByTessella Support Services plc


Aelan Cell Technologies publishes new research identifying biomarkers that could serve as companion diagnostics for patients being treated with IL-2

Aelan Cell Technologies publishes new research identifying biomarkers that could serve as companion diagnostics for patients being treated with IL-2

The collaborative study was performed by modeling the aging of MSCsex-vivo, through a process called replicative senescence. The research highlights the possibility that in younger patients IL-2s and MSCs work in conjunction to fight cancer. ...

ByAelan Cell Technologies


Cytotoxicity of activated natural killer cells against pediatric solid tumors

Cytotoxicity of activated natural killer cells against pediatric solid tumors

We sought to identify the most sensitive tumor subtypes, clarify the molecular interactions regulating cytotoxicity, and determine NK antitumor potential in vivo. Experimental design: We tested in vitro cytotoxicity of expanded NK cells against cell lines representative of Ewing sarcoma (EWS; n = 5), rhabdomyosarcoma (n = 4), neuroblastoma (n = 3), and ...

ByNkarta, Inc.

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