Inflammation Improve Articles & Analysis
6 articles found
Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), represents a significant challenge in healthcare due to its detrimental impact on lung function and limited treatment options. While WNT/β-catenin signaling plays a crucial role in lung development and maintenance of adult lung stem cells, its dysregulation has been associated with pulmonary fibrosis. However, recent ...
Li et al constructed a novel siRNA delivery system sTOLP(loaded with siRNAOA-R8 / TF-modified LNP) for cell penetrating peptioyl-octadecarginine (OA-R8) transferrin (Tf)-modified multifunctional lipid nanoparticles (LNP). siRNA encapsulated in sTOLP showed strong tumor inhibition (61.7%) and was preferentially absorbed by hepatocytes and tumor cells in HepG2-containing mice without inducing ...
Probiotics for gut health help to increase the number of beneficial bacteria in the gut, which can enhance the immune system, improve digestion, and alleviate some health conditions. Probiotics can also produce antimicrobial substances, which can inhibit the growth of harmful bacteria in the gut. ...
In addition, drug activity was also observed in paclitaxel-resistant cells. 3. Targeted Treatment of Inflammation The nuclear transcription factor kappaB (NF-κB) is a vital transcriptional regulator in cells. ...
In addition, it also has the effect of improving atherosclerosis, myocardial energy metabolism and anti-fibrosis. 3. ...
When Roseburia spp. are administered to ALD murine models, both hepatic steatosis and inflammation significantly improve regardless of bacterial viability. Specifically, the flagellin of R. intestinalis, possibly through Toll-like receptor 5 (TLR5) recognition, recovers gut barrier integrity through upregulation of the tight junction protein Occludin and helps to ...