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Inflammatory Skin Articles & Analysis

8 articles found

The Vital and Complex Role of Elastase

The Vital and Complex Role of Elastase

It is involved in the breakdown of invading microorganisms and cellular debris during inflammatory responses. By degrading harmful entities, elastase helps in modulating immune responses and tissue repair. ...

ByCreative Enzymes


Mechanisms to Combat Drug Resistance: Overview of Antimicrobial Peptides

Mechanisms to Combat Drug Resistance: Overview of Antimicrobial Peptides

In addition to their direct antimicrobial effects, some AMPs can modulate immune responses, enhancing phagocytosis and even exhibiting anti-inflammatory properties for localized treatment of skin infections, respiratory infections, and systemic infections. ...

ByBOC Sciences


Unraveling the IL-17 Family and its Receptor Complex: Key Players in Immune Responses

Unraveling the IL-17 Family and its Receptor Complex: Key Players in Immune Responses

IL-17 ligands produce organ-specific pro-inflammatory or anti-inflammatory responses through their corresponding receptors. ...

ByBeta Lifescience


Understanding IL-36 Cytokines: Their Role & Potential in Treating Inflammatory Diseases

Understanding IL-36 Cytokines: Their Role & Potential in Treating Inflammatory Diseases

The binding of IL-36 Ra to IL-1R6 does not lead to the recruitment of IL-1RAcP. Therefore, the pro-inflammatory cascade reaction is not initiated, realizing the anti-inflammatory characteristics of IL-36 Ra. IL-38 also binds to IL1R6 and has anti-inflammatory effects similar to IL-36 Ra. IL-36 is mainly distributed in skin, ...

ByBeta Lifescience


Reconstruction of tissues affected by Pilonidal Sinus Disease

Reconstruction of tissues affected by Pilonidal Sinus Disease

Only one minor postoperative wound complication was observed that went on to resolve without requiring any additional surgical intervention. PSD is a chronic inflammatory disease affecting the soft tissue of the buttock cleft resulting in long term non-healing wounds that are hard to heal and challenging for clinicians to treat. ...

ByAroa Biosurgery Limited


COVID-19: We all have skin in the game

COVID-19: We all have skin in the game

Blueberry Therapeutics is a drug development company committed to finding new and improved treatments for a range of dermatological conditions affecting the skin and nails. The future and long-term effect of the global COVID-19 pandemic (caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2 virus]) on dermatology practice and skin health is still unknown, but here we provide some ...

ByBlueberry Therapeutics


Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota

Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota

KBL382 treatment modulates TSLP, pro-inflammatory chemokines, and cytokines in dorsal skin lesions The levels of TSLP, TARC, and MDC were significantly reduced in KBL382-treated mice compared to DFE+PBS mice (Figure 4A–C). ...

ByKoBioLabs


Administration of Lactobacillus fermentum KBL375 Causes Taxonomic and Functional Changes in Gut Microbiota Leading to Improvement of Atopic Dermatitis

Administration of Lactobacillus fermentum KBL375 Causes Taxonomic and Functional Changes in Gut Microbiota Leading to Improvement of Atopic Dermatitis

Significant reductions in mast cells and eosinophils were discovered in skin tissues from L. fermentum KBL375-treated mice. T helper 2 cell-related cytokines interleukin (IL)-4, IL-5, IL-13, and IL-31 significantly decreased, and anti-inflammatory cytokine IL-10 or transforming growth factor-β increased in skin tissues from L. fermentum ...

ByKoBioLabs

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