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Influenza Infected Articles & Analysis

10 articles found

Flu, COVID-19, and RSV in the U.S.: Insights from the Latest Surveillance Season

Flu, COVID-19, and RSV in the U.S.: Insights from the Latest Surveillance Season

Welcome to 2023-2024 season’s respiratory surveillance recap, where we’ll share insights from the most recent respiratory surveillance season, covering three major respiratory viruses: COVID-19, influenza, and RSV. Tracking these illnesses is imperative for maintaining population health because these illnesses significantly impact individual wellbeing and healthcare costs, resource ...

ByBiobot Analytics, Inc.


Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2

Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2

The recent COVID-19 pandemic again highlighted the urgent need for broad-spectrum antivirals, both for therapeutic use in acute viral infection and for pandemic preparedness in general. The targeting of host cell factors hijacked by viruses during their replication cycle presents one possible strategy for development of broad-spectrum antivirals. By inhibiting the Raf/MEK/ERK signaling pathway, ...

ByAtriva Therapeutics GmbH


API - Oseltamivir Phosphate

API - Oseltamivir Phosphate

Introduction Oseltamivir phosphate is a white or almost white crystalline powder with the chemical name ethyl(3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-cyclohex-1-ene-1-carboxylate phosphate. It is an influenza viral neuraminidase inhibitor used in the prevention and treatment of influenza. Application in the treatment of influenza Introduction of influenza Influenza, also called flu or ...

ByAlfa Chemistry


Organoid Models of SARS-CoV-2 Infection learned from COVID-19

Organoid Models of SARS-CoV-2 Infection learned from COVID-19

The clinical presentation of COVID-19-related illness ranges from asymptomatic to mild respiratory symptoms resembling influenza infection to acute symptoms including pneumonia requiring hospitalization and admission to the intensive care unit. COVID-19 starts in the upper airways and lungs, but in severe cases can also affect the heart, blood vessels, brain, liver, kidneys, and intestines. ...

ByCreative Bioarray


Ozette’s AI in the battle against Covid - Case study

Ozette’s AI in the battle against Covid - Case study

Summary The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic began in 2019 and rapidly scaled to a global presence of disease known as COVID-19. Despite the relatively fast implementation of testing and vaccination worldwide, the rise of emerging viral variants and breakthrough infections raises concerns that SARS-CoV-2 will continue to pose a global health threat. ...

ByOzette Technologies


FluGen Announces Completion of First Cohort in Age De-escalation Clinical Trial of M2SR Flu Vaccine Candidate in Pediatric Subjects Ages 6 Months to 17 Years

FluGen Announces Completion of First Cohort in Age De-escalation Clinical Trial of M2SR Flu Vaccine Candidate in Pediatric Subjects Ages 6 Months to 17 Years

MADISON, Wis., Sept. 7, 2022 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine efficacy in infectious respiratory diseases, today announced the completion of enrollment of the first cohort in an age de-escalation clinical trial of M2SR (M2 Deficient Single Replication) live virus vaccine, the company’s investigational supra-seasonal intranasal ...

ByFluGen, Inc.


Nature Biotechnology: Generation of a live attenuated influenza A vaccine by proteolysis targeting

Nature Biotechnology: Generation of a live attenuated influenza A vaccine by proteolysis targeting

Longlong Si's research group from the Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, published a research titled "Generation of a live attenuated influenza A vaccine by proteolysis targeting" in Nature Biotechnology. Using influenza virus as a model virus, the team established the technology of protein degradation targeting virus as an ...

ByProfacgen


Creative Enzymes Launches Advanced Neuraminidase for Flu Vaccine Development

Creative Enzymes Launches Advanced Neuraminidase for Flu Vaccine Development

Creative Enzymes, a professional enzyme provider located in New York, always hammers at researches and trials in order to provide customers with various enzymes as many as possible. Last week, the product manager of Creative Enzymes announced the launch of neuraminidase, which is expected to further develop a new universal influenza vaccine. Neuraminidase is a drug target to prevent the spread ...

ByCreative Enzymes


Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Abstract Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as a popular recreational tool among adolescents and adults. Although the use of ENDS is often promoted as a safer alternative to conventional cigarettes, few comprehensive studies have assessed the long-term effects of vaporized nicotine and its associated solvents, propylene glycol (PG) and vegetable glycerin ...

ByJohnson Controls, Inc.


Simulation to assess the efficacy of US airport entry screening of passengers for pandemic influenza

Simulation to assess the efficacy of US airport entry screening of passengers for pandemic influenza

We present our methodology and stochastic discrete-event simulation developed to model the screening of passengers for pandemic influenza at the US port-of-entry airports. Our model uniquely combines epidemiology modelling, evolving infected states and conditions of passengers over time, and operational considerations of screening in a single simulation. The simulation begins with international ...

ByInderscience Publishers

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