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Injectable Drug Articles & Analysis
25 articles found
In the process of new drug development, the study of pharmacokinetics is of great significance. The result can be used to guide the screening and development of drugs, and support the evaluation of their safety and the design of clinical drug delivery protocol. ...
This structure mimics the cell membrane, allowing liposomes to seamlessly interact with cells. Why use liposomes for drug delivery? Traditional drug delivery methods, like pills and injections, often have drawbacks. ...
These biocompatible, water-swollen structures are formed with the incorporation of drug-loaded microspheres or nanoparticles. Their porous nature allows the sustained release of drugs, enhancing therapeutic efficacy. ...
Subsequent studies found that this LNP, when loaded with mRNA encoding a broadly neutralizing antibody against coagulase, could protect mice from H1N1 influenza infection. 3) Local injection refers to the administration of drugs to a small area of the body. These drugs can affect not only the local site but also diffuse or transfer to the ...
These innovative patches provide a minimally invasive and painless alternative to injections while ensuring precise and controlled drug administration. In this article, we will explore various types of microneedle patch technologies, including phase-transition microneedle patches, hydrogel microneedle patches, solid microneedles, hollow microneedles, coated ...
On February 24, 2023, The NMPA approved Enhertu, an injectable drug developed jointly by AstraZeneca and Daiichi Sankyo, for the treatment of adults with unresectable or metastatic HER2-positive breast cancer who have previously received one or more anti-HER2 drugs. Dertrastuzumab is an antibody-drug conjugate (ADC) ...
The GLP-1 analogues have established themselves in the past years as one of the superior drug classes for treatment of diabetes type II in terms of blood glucose lowering and weight loss. Because of the latter, they are being used more and more also in the treatment of obesity. Until now, both drugs are only available by injection. With the ...
Therefore, patients need to take a lot of drugs, which seriously affects their quality of life. The emergence of semaglutide, a new GLP-1RA weekly preparation, has brought hope to patients with diabetes. ...
If insulin alone does not work to keep blood sugar levels stable in type 1 diabetes patients, it may be supplemented with Amylinomimetic drugs that are injected before meals to delay the time it takes your stomach to digest food. ...
Sanofi-backed Enable Injections has gone big with its series C round. Three years after Sanofi led its series B, Enable Injections has raised a $215 million round to fund work on subcutaneous drug delivery system enFuse. Enable Injections’ device consists of a wearable delivery disc and a system for transferring the ...
It can be said that without excipients, there will be no pharmaceutical preparations, let alone different pharmaceutical dosage forms such as powders, granules, tablets, oral liquids or injections. When the drug and the appropriate excipients are combined into a specific dosage form, the drug would become safer, more stable and more convenient to ...
Typical biologic concentrations are ≤200 mg/mL; with increased dose needs there becomes a trade-off between concentration which leads to higher drug volume or viscosity, which results in drug-delivery solutions that either take more time or force to inject. ...
Blueberry were recently invited to write two commentaries on the challenges of treating skin and nail diseases and the potential for nanotechnology approaches in dermal drug delivery. Here we share a brief overview of these articles. We will all have encountered someone who is dealing with or has previously experienced a common ailment of the skin or nails, such as eczema (atopic dermatitis), ...
It can be said that without excipients, there will be no pharmaceutical preparations, let alone different pharmaceutical dosage forms such as powders, granules, tablets, oral liquids or injections. When the drug and the appropriate excipients are combined into a specific dosage form, the drug would become safer, more stable and more convenient to ...
Biologics are among the top-selling therapeutics on the market, making up eight of the top 10 selling drugs. All biologics are injected using either subcutaneous, intramuscular or intravenous routes. ...
Pharmaceutical excipients have important functions such as serving as carriers, improving drug stability, solubilization and slowing down the drug release. They are important ingredients that may affect the quality, safety, and effectiveness of the preparation. Classified by function and purpose, pharmaceutical excipients can be used in different ...
There is evidence for some conditions suggesting patients prefer oral drugs to injections: for example, studies on cancer patients have illuminated patient preference for oral therapies rather than regular injections. ...
Rani Therapeutics offers a breakthrough capsule, the RaniPill which could change the way patients with chronic conditions take medication by eliminating the need for painful injections. Rani Therapeutics is a clinical-stage biotherapeutics company offering an alternative to painful injections for patients with chronic conditions such as neuroendocrine ...
Antibody-drug conjugates (ADCs) continue to rise at home and abroad, but ADCs are not a new thing. ...
“That’s in line with subcutaneous injections, which ranged between 40% and 80%,” said Talat Imran, the company’s CEO. “Based on that and our plans for the rest of the drugs in our pipeline, we felt like it was the right time to go ...