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Intestinal Development Articles & Analysis

3 articles found

Function and Detection of Bile Acids

Function and Detection of Bile Acids

Primary bile acids are secreted into the intestine and undergo 7α dehydroxylation by intestinal bacteria to form secondary bile acids. ...

ByCreative Proteomics


Development of new levodopa treatment strategies in Parkinson`s disease-from bedside to bench to bedside

Development of new levodopa treatment strategies in Parkinson`s disease-from bedside to bench to bedside

Abstract This review will illustrate the process of moving from an idea through preclinical research and Galenic developments into clinical investigations and finally to approval by regulatory agencies within the European Union. The two new treatment strategies described, levodopa/carbidopa intestinal gel and levodopa/carbidopa microtablets, for advanced ...

BySensidose AB


Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice

Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice

Mice carrying Apc mutations in their germ line (ApcMin) develop intestinal adenomas. Here, the crossing of ApcMin with cyclin D1–/– mice reduced the intestinal tumor number in animals genetically heterozygous or nullizygous for cyclin D1. Decreased tumor number in the duodenum, intestines, and colons of ApcMin/cyclin D1+/– mice ...

ByAmerican Society for Microbiology (ASM)

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