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Intestinal Lumen Articles & Analysis

6 articles found

Understanding Caco-2 Permeability Assay: A Critical Tool for Drug Development

Understanding Caco-2 Permeability Assay: A Critical Tool for Drug Development

One of the most widely recognized in vitro models for evaluating the intestinal absorption of compounds is the Caco-2 permeability assay. This assay plays a pivotal role in understanding how drugs are absorbed in the gastrointestinal tract and aids in predicting their bioavailability. ...

ByCreative Bioarray


Regulation of Lipid Metabolism in the Intestinal Flora

Regulation of Lipid Metabolism in the Intestinal Flora

Enteroendocrine cells have an apical membrane facing the intestinal lumen that allows them to interact with microorganisms and their metabolites. ...

ByCreative Proteomics


The Importance of Moderate Supplementation of Intestinal Lactase

The Importance of Moderate Supplementation of Intestinal Lactase

Lactase is a disaccharidase present on the surface of mammalian small intestinal mucosal microvilli, and many beneficial intestinal bacteria have the ability to produce lactase. ...

ByCreative Enzymes


Human Intestinal Ecosystem Analysis

Human Intestinal Ecosystem Analysis

The large intestine is composed of intestinal epithelial cells (IECs), which form an intestinal barrier between the microbiota in the intestinal lumen and surrounding tissues. ...

ByCreative Proteomics


How Does Altis Biosystems Envision the Future of the Pharma/Biopharma Industry?

How Does Altis Biosystems Envision the Future of the Pharma/Biopharma Industry?

Human intestinal stem cells, by contrast, are already epigenetically modified to limit them to a range of differentiated types but are then free to form the appropriate diversity of intestinal epithelial cell types. ...

ByAltis Biosystems


Evaluating Microbiome Therapies with Intestinal Cell Models

Evaluating Microbiome Therapies with Intestinal Cell Models

Intestinal and Colonic Stem Cells and Disease Stem cells are implicated in a variety of disease process. ...

ByAltis Biosystems

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