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Kidney Dysfunction Articles & Analysis

6 articles found

Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor

Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor

Ferrostatin-1 inhibits cell death in cellular models of Huntington's disease (HD), periventricular leukomalacia (PVL), and kidney dysfunction[2]. Ferrostatin-1 (1 μM; 6 h) inhibits the oxidative destruction of unsaturated fatty acids in HT-1080 cells, thus increases the number of healthy medium spiny neurons ...

ByMedChemExpress LLC (MCE)


Cytokine Involvement in Inflammatory Immune Disorders

Cytokine Involvement in Inflammatory Immune Disorders

Inflammatory effectors are key cytokines driving major clinical symptoms, like INF-γ inducing fever and hematopoiesis, TNF-α causing fever and depression, and IL-6 contributing to fever, acute kidney injury, and NK cell dysfunction. Inflammation initiation factors involve virus recognition by macrophage pattern receptors, triggering inflammasome ...

ByCreative Proteomics


What causes heart failure with preserved ejection fraction (HFpEF)?

What causes heart failure with preserved ejection fraction (HFpEF)?

Heart failure with preserved ejection fraction (HFpEF) is a multifactorial and multisystemic disorder that represents more than 50% of all heart failure cases.[1] Epidemiologic data from the Framingham Study, an international cohort study, shows a rapid increase in the prevalence of HFpEF over the past three decades, from 41% to 56% and, conversely, a decrease in the prevalence of HFrEF from 44% ...

ByUltromics Limited


A translational study of Galectin-3 as an early biomarker and potential therapeutic target for ischemic-reperfusion induced acute kidney injury

A translational study of Galectin-3 as an early biomarker and potential therapeutic target for ischemic-reperfusion induced acute kidney injury

Abstract Purpose: We evaluated Galectin-3 (Gal-3) as a potential early biomarker of acute kidney disease (AKI), and the effect of Gal-3 inhibition by modified citrus pectin (P-MCP) on renal ischemia/reperfusion (I/R) induced AKI. ...

ByEliaz Therapeutics


How to support healthy blood sugar levels.

How to support healthy blood sugar levels.

Maintaining healthy blood sugar levels can help reduce the risk of developing diabetes, kidney dysfunction, and problems with your eyes, gums, and nerves. Day-to-day healthy blood sugar levels will help with balancing energy levels, maintaining focus, and stabilizing mood. ...

ByAmyris Biotechnologies, Inc.


3 Things That Google’s Healthcare Artificial Intelligence Desperately Needs

3 Things That Google’s Healthcare Artificial Intelligence Desperately Needs

Google DeepMind recently published a paper in Nature that shared how their predictive algorithm can detect Acute Kidney Injury (AKI) up to 48 hours in advance. Acute Kidney Injury is the biggest problem you have never heard of. ...

ByPotrero Medical

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