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Laboratory Animal Articles & Analysis: Older

6 articles found

Highlight the Everolimus metabolic effects on breast cancer

Highlight the Everolimus metabolic effects on breast cancer

In contrast, metformin has little effect on glycolysis products, another energy-producing process, both in the laboratory and in animals. The use of Precellys Evolution* helped to measure different TCA and glycolysis products, which in turn enabled us to understand how everolimus and metformin affect mitochondrial activity under different conditions, using ...

ByBertin Technologies


Spatial profiling of chromatin accessibility in mouse and human tissues

Spatial profiling of chromatin accessibility in mouse and human tissues

MethodsJuvenile mouse brain and sample preparation Experimental procedures on juvenile (P21) mice were conducted in accordance with the European directive 2010/63/EU, local Swedish directive L150/SJVFS/2019:9, Saknr L150 and the Karolinska Institutet complementary guidelines for procurement and use of laboratory animals, Dnr 1937/03-640. The procedures described ...

ByAtlasXomics Inc.


Nipah virus glycoprotein structure suggests therapeutic strategies

Nipah virus glycoprotein structure suggests therapeutic strategies

It is estimated that 200 million people in the world live in areas where the transmission of henipaviruses by bat or animal vectors may pose a threat. The lead author of the latest Henipah virus paper in Science is David Weiler, an associate professor of biochemistry at Washington University School of Medicine and a Howard Hughes Medical Fellow. ...

ByCreative Biostructure


UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine

UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine

Refinement of the CoroFlu vaccine concept and testing in laboratory animal models at UW–Madison is expected to take three to six months. ...

ByFluGen, Inc.


Vaginal lactobacilli inhibit growth and hyphae formation of Candida albicans

Vaginal lactobacilli inhibit growth and hyphae formation of Candida albicans

DNA extraction and 16S rRNA sequencing analysis Total genomic DNA was extracted from vaginal swabs using a PowerSoil® DNA Isolation Kit (MO BIO Laboratories, Inc., Carlsbad, CA, USA) according to the manufacturer’s instructions with minor modifications39. ...

ByKoBioLabs


Neutron capture therapy at the MEPhI reactor

Neutron capture therapy at the MEPhI reactor

The article discusses the results of the creation and development of the irradiation base for Neutron Capture Therapy (NCT) at the MEPhI Reactor, development and studies of boron- and gadolinium-containing compounds, and presents the results of pre-clinical NCT studies in large laboratory animals – dogs with spontaneous melanoma.Keywords: nuclear reactors, ...

ByInderscience Publishers

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