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Lower Extremity Articles & Analysis

17 articles found

Peptides for Osteoporosis Research

Peptides for Osteoporosis Research

Introduction to OsteoporosisOsteoporosis is a systemic multi-causal skeletal disease that is prone to fractures due to changes in systemic bone mass and microstructure of bone tissue, resulting in increased bone fragility. Osteoporosis is a type of disease that is difficult to cure. According to the etiology, it can be divided into primary osteoporosis, secondary osteoporosis and idiopathic ...

ByBOC Sciences


Will Metformin Be Replaced By SGLT-2 Inhibitors

Will Metformin Be Replaced By SGLT-2 Inhibitors

Metformin is a classic first-line hypoglycemic agent for patients with type 2 diabetes, and is an essential drug in combination regimenes. However, as the evidence is updated, the idea of drug selection for first-line treatment is changing. GLP-1 agonists and SGLT-2 inhibitors in combination with or without metformin (as required for glycemic management) have also been recommended by multiple ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Diagnosing heart failure with preserved ejection fraction (HFpEF)

Diagnosing heart failure with preserved ejection fraction (HFpEF)

Heart failure with preserved ejection fraction (HFpEF) has recently been recognized as the single greatest unmet need in cardiovascular medicine, overtaking heart failure with reduced ejection fraction (HFrEF) and becoming the most common form of heart failure, with a prevalence that is increasing by 1% annually.[1] Despite this, there remains no gold standard in diagnosing HFpEF. Diagnosing ...

ByUltromics Limited


Pelvic Ring Injury in Polytrauma Treatment with the Curvafix IM System - Case Study

Pelvic Ring Injury in Polytrauma Treatment with the Curvafix IM System - Case Study

CASE PLANNING The bilateral upper extremity fractures, the pre-existing contralateral lower limb amputation with loss of the prosthesis, and the patient's need for immediate weight bearing on her right lower extremity were all considerations in proceeding with pelvic ring fixation using two CurvaFix IM Implants. Combined fixation of the anterior ring and the posterior ring provides the greatest ...

ByCurvaFix, Inc.


Alucent Biomedical Re-Envisioning PAD Treatment with a Natural Vascular Scaffold

Alucent Biomedical Re-Envisioning PAD Treatment with a Natural Vascular Scaffold

Start-up Alucent Biomedical is using a light-activated molecule, delivered via a balloon catheter, to create a natural vascular scaffold in diseased peripheral vessels, with the aim of providing a long-lasting treatment option that maintains patency while leaving nothing behind in the vessel. Alucent Biomedical Inc. is rethinking peripheral artery disease (PAD) treatment with a novel natural ...

ByAlucent Biomedical Inc.


Solutions Built to Cure - Case study

Solutions Built to Cure - Case study

Whether you are a physiotherapist who is treating a patient or someone who would like to receive rehabilitation safely at home, BECURE is ready to help you. The Problem Physiotherapy (physical therapy) is used for the rehabilitation of neurological, orthopedic, pediatric, geriatric, and rheumatologic diseases; to diagnose muscle-skeletal system diseases; and to treat them. It is a holistic ...

ByBeCure


Clinical implementation of the Humacyte human acellular vessel: Implications for military and civilian trauma care

Clinical implementation of the Humacyte human acellular vessel: Implications for military and civilian trauma care

ABSTRACT: The incidence of wartime vascular injury has increased and is a leading cause of mortality and morbidity. While ligation remains an option, current resuscitation and damage control techniques have resulted in vascular repair being pursued in more than half of wartime injuries. Options for vascular reconstruction are currently limited to autologous vein or synthetic conduits, choices ...

ByHumacyte, Inc.


Sit to Stand balance protocol, how to use it?

Sit to Stand balance protocol, how to use it?

A look at the Sit-to-Stand protocol The Sit-to-Stand (STS) is a well-known test to quantify the ability of the patient to lift from a sitting position to a standing position. The STS maneuver is mainly used to assess lower limb strength, balance and also fall risk in elderly people [1]. There are several variations of the STS test, such as the five-repetition STS test (FRSTST) which report ...

BySensing Future Technologies


Lower Extremity Amputations: Why, What Kind, & Life After

Lower Extremity Amputations: Why, What Kind, & Life After

Every year, surgeons perform a lower-limb amputation due specifically to diabetes on approximately 73,000 patients in the US alone. Annually there are over 1 million limb amputations worldwide. Most of these amputations are performed for the treatment of non-healing diabetic foot ulcers that resulted from PAD (Peripheral Arterial Disease). These non-healing foot ulcers are caused by high blood ...

ByEO2 Concepts


Cost-Effectiveness of Percutaneous Deep Vein Arterialization for Patients with No-Option Chronic Limb-Threatening Ischemia: an Exploratory Analysis Based on the PROMISE I Study

Cost-Effectiveness of Percutaneous Deep Vein Arterialization for Patients with No-Option Chronic Limb-Threatening Ischemia: an Exploratory Analysis Based on the PROMISE I Study

Abstract Background. As the most advanced stage of peripheral arterial disease (PAD), chronic limb-threatening ischemia (CLTI) is associated with a high risk of lower-limb loss and mortality. Percutaneous deep vein arterialization (pDVA) is a promising new treatment alternative for CLTI patients who cannot be treated with conventional revascularization techniques. Our study objective was to ...

ByLimFlow, Inc.


Surgical management of an infected external iliac artery interposition graft with a bioengineered human acellular vessel

Surgical management of an infected external iliac artery interposition graft with a bioengineered human acellular vessel

ABSTRACT Infection of prosthetic vascular grafts can manifest as pain, pseudoaneurysms, or arterial insufficiency in the leg. We present the case of a female patient with a medical history of a right external iliac artery endofibrosis, with a persistently infected synthetic iliofemoral bypass graft, which we replaced with a bioengineered human acellular vessel. At the 12-month follow-up visit, ...

ByHumacyte, Inc.


LimFlow Percutaneous Deep Venous Arterialization

LimFlow Percutaneous Deep Venous Arterialization

What interested you in LimFlow, and how did you get involved in the PROMISE I trial? Dr. Clair: Practicing vascular surgery, where a number of patients are evaluated for chronic limb-threatening ischemia (CLTI), you are guaranteed to have patients who are not candidates for percutaneous or surgical revascularization. These patients often have arterial systems open or identifiable to the ankle, ...

ByLimFlow, Inc.


A Paradigm Shift in the Treatment of Venous Thromboembolic Disease

A Paradigm Shift in the Treatment of Venous Thromboembolic Disease

PE is the most common preventable cause of death among hospital patients in the United States. VTE is a leading cause of death and disability worldwide and has the third-highest mortality rate out of any cardiovascular disease, behind myocardial infarctions and stroke. Unlike myocardial infractions and stroke, where mortality has improved considerably, VTE has seen an increase in cases, with no ...

ByThrombolex, Inc.


Innovation Spotlight: Alucent Biomedical | Can we Make ‘Stents’ Obsolete?

Innovation Spotlight: Alucent Biomedical | Can we Make ‘Stents’ Obsolete?

As part of our ongoing Vascular Innovation Series in conjunction with The Way to My Heart, journalist Kym McNicholas interviewed Alucent Biomedical CEO, Dr. Myles Greenberg. Treatment for vascular blockages is getting a much-needed innovation makeover. Alucent’s first area of focus is one the most debilitating vascular diseases –peripheral artery disease, plaque build-up in mainly ...

ByAlucent Biomedical Inc.


The Evolving Role of Percutaneous Deep Venous Arterialization

The Evolving Role of Percutaneous Deep Venous Arterialization

The increasing incidence of peripheral artery disease (PAD) is occurring globally as populations age and rates of diabetes, obesity, and renal disease increase.1-3 Although most of these patients have no symptoms, when the disease progresses to its most advanced form, chronic limb-threatening ischemia (CLTI), there is a significant risk for limb loss. Despite the fact that our revascularization ...

ByLimFlow, Inc.


Effects of supervised high-intensity resistance and impact training or machine-based isometric training on regional bone geometry and strength in middle-aged and older men with low bone mass: The LIFTMOR-M semi-randomised controlled trial

Effects of supervised high-intensity resistance and impact training or machine-based isometric training on regional bone geometry and strength in middle-aged and older men with low bone mass: The LIFTMOR-M semi-randomised controlled trial

Abstract Introduction: Few data exist on the effects of bone-targeted exercise on geometric and biomechanical indices of bone strength in men. The Lifting Intervention For Training Muscle and Osteoporosis Rehabilitation for Men (LIFTMOR-M) trial was designed to compare the efficacy and safety of two novel, supervised, twice-weekly, high-intensity exercise programs in middle-aged and older ...

By3D-Shaper Medical SL


A Treatment Proposal with Lower Extremity Robotic Devices: Performance of Postural Analysis and Determination of Exercises Using the REX Robot

A Treatment Proposal with Lower Extremity Robotic Devices: Performance of Postural Analysis and Determination of Exercises Using the REX Robot

Exercise is an intervention commonly used in the management of multiple sclerosis (MS). The more recent understanding is that exercise is a very important part of maintaining functional independence in individuals with MS. Many studies and research has shown that properly prescribed exercise programs can decrease impairments in MS, as well as improving activities of daily living, and quality of ...

ByRex Bionics Ltd

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