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Lung Fibrosis Articles & Analysis

6 articles found

CCR1 Protein: A Chemokine Receptor at the Crossroads of Immunity and Disease

CCR1 Protein: A Chemokine Receptor at the Crossroads of Immunity and Disease

Recombinant CCR1 is a key platform to unravel this bias, with implications for drug design. l CCR1 in Fibrosis: Beyond immune recruitment, CCR1 contributes to fibroblast activation in liver, kidney, and lung fibrosis. ...

ByCreative BioMart


Shaping the Future of Pulmonary Fibrosis Therapy with Inhaled Microgels

Shaping the Future of Pulmonary Fibrosis Therapy with Inhaled Microgels

Idiopathic pulmonary fibrosis (IPF) is a devasting lung disease characterized by progressive scarring of lung tissue. As fibrosis develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. ...

BySCIREQ - an emka TECHNOLOGIES Company


Benefits of point of care PFT in Rural Health

Benefits of point of care PFT in Rural Health

For example, one study found that only 34.5% of Americans living in rural areas had access to a pulmonologist within 10 miles of their home, compared with 97.5% of those living in more urban areas.2 A similar study described the same lack of access to imaging services, finding that 77.8% of patients eligible for lung cancer screening had to drive more than 30 minutes to find a ...

ByNDD Medical Technologies


Computer Vision-Based Digital Biomarkers Could Enable Faster and More Accurate In Vivo Assessment of Disease

Computer Vision-Based Digital Biomarkers Could Enable Faster and More Accurate In Vivo Assessment of Disease

‍‍ As an example, breathing is a key functional endpoint in patients with lung fibrosis. As the severity of fibrosis increases, elastic and functional tissue in the lungs is replaced with inelastic scar tissue, which makes breathing a challenge. ...

ByRecursion


When in Rome—SOT Funding Enables Training in Isolating and Culturing Mesenchymal Stem Cells

When in Rome—SOT Funding Enables Training in Isolating and Culturing Mesenchymal Stem Cells

I presented part of my doctoral research on how macrophages play a regulatory role in lung injury and fibrosis. During the meeting, I had several conversations with Dr. ...

BySociety of Toxicology


Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles

Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles

Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease. A maladaptive epithelium due to chronic injury is a prominent feature and contributor to pathogenic cellular communication in IPF. Recent data highlight the concept of a “reprogrammed” lung epithelium as critical in the development of lung ...

ByJohnson Controls, Inc.

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