Lung Inflammation Articles & Analysis
6 articles found
The enzyme can degrade structural proteins in the lung, vasculature, and connective tissue. Key pathologies associated with excessive ELANE activity include: l Chronic obstructive pulmonary disease (COPD): ELANE-mediated degradation of lung elastin contributes to alveolar destruction and emphysema. l Cystic fibrosis (CF): Neutrophilic ...
Quite often the person knows what sets their symptoms off. How does asthma affect the lungs? Asthma causes an inflammation of the mucous membrane, which can lead to swelling into the airspace, increase in mucous production, twitch airways and bronchospasms. ...
Overactive elastase can cause excessive breakdown of elastin, leading to diseases such as emphysema, where the alveoli in the lungs lose their elasticity, and various skin disorders marked by premature aging or loss of elasticity. ...
Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells (UC-MSCs) to block the life-threatening lung inflammation that accompanies severe cases of COVID-19. The therapy uses cells from discarded umbilical cords, with just one cord saving as ...
Here, we show that compared with smoke exposure, mice receiving ENDS vapor for 4 months failed to develop pulmonary inflammation or emphysema. However, ENDS exposure, independent of nicotine, altered lung lipid homeostasis in alveolar macrophages and epithelial cells. ...
Examples of applications are given in the context of the acute respiratory distress syndrome (ARDS), an inflammatory disease of the lung triggered by a massive arrest of white blood cells in the lung microvasculature. ...