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Mammalian Cell Culture Articles & Analysis

3 articles found

Single-Domain Antibody Production: A Comprehensive Overview

Single-Domain Antibody Production: A Comprehensive Overview

They can be produced in microbial systems such as yeast or bacteria, which reduce the complexity and cost associated with mammalian cell culture. Reduced Immunogenicity: Due to their smaller size and unique structure, single-domain antibodies tend to elicit a lower immune response in humans, making them safer for therapeutic applications. ...

ByCreative Biogene


Module 3: Culture Medium

Module 3: Culture Medium

Don’t worry too much about it. The culture medium is probably the most important cell culture component, as it provides the liquid environment and nutrients that cells need to stay alive. ...

ByAgulos Biotech, LLC


The Problem with Gene-Modified Cell Therapy Manufacturing

The Problem with Gene-Modified Cell Therapy Manufacturing

Gene-modified cell therapies (GMCTs) represent the most effective therapeutic platform for many patients with advanced diseases including relapsed and refractory leukemia, non-Hodgkin lymphoma, and other blood cancers [1]. Specifically, chimeric antigen receptor T cell (CAR-T) therapies targeting CD19 have demonstrated remarkable responses and possibly cures in patients with advanced acute ...

ByIndee Labs

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