Melanoma Model Articles & Analysis
4 articles found
The IP10-loaded platelets targeted and inhibited tumor cells in the B16F10 melanoma model and lessened immunosuppressive regulatory T cell activity through CD40L activation on platelet membranes which led to boosted anti-tumor immunity. ...
Researcher Insco said that we found that CDK13 protein can play the role of tumor suppressor in melanoma, and its mutation or deletion can lead to tumor occurrence. By analyzing the data of melanoma patients and the Zon zebrafish model, the researchers clarified that the reason for inducing CDK13 protein deletion or mutation, and revealed its ...
More importantly, this new therapy has been validated in mouse solid tumor models of melanoma and pancreatic cancer, providing new strategies for the study and application of adoptive T cells in the treatment of solid tumors. ...
The influence of repeated 0.5 Gy whole-body gamma-ray irradiation on tumour metastasis was examined from the standpoint of tumour invasion in the B16 melanoma pulmonary metastasis model in mice. We confirmed that 0.5 Gy whole-body gamma-ray irradiation (four doses over two weeks) significantly suppressed colony formation in the lungs. ...