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Metabolic Clinical Articles & Analysis
3 articles found
The human gut microbiota has a large gene pool, encoding approximately 100-150 times more genes than the human genome, and contains a rich resource of enzymes with the ability to metabolize drugs. The diversity of gut bacteria also affects the mental health of the host. ...
We have proposed a novel combinatorial approach using FDA approved compounds targeting IL-17a and DPP4 to ameliorate a significant portion of the clustered clinical risks in patients with metabolic syndrome. In our current research we have modeled the outcomes of metabolic syndrome treatment using two distinct drug classes. Methods Targets were ...
Supplementary Tables 1 and 2 present the detailed characteristics of each group, including clinical, metabolic, biochemical, and histological profiles. Subjects with NASH or significant fibrosis (F2–4) had higher levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and insulin resistance in both the obese and non-obese groups. ...