Metabolic Gene Articles & Analysis
8 articles found
The increasing application of Lactobacillus species in biotechnology, pharmaceutical sciences, and clinical research has necessitated a more nuanced understanding of strain-specific characteristics and formulation parameters. This is particularly relevant for researchers working with lactobacillus acidophilus powder and selecting appropriate lactobacillus strains for specialized applications. ...
Fatty acids, along with glucose and amino acids, are the main source of energy for cell growth and proliferation. Abnormalities in fatty acid metabolism are commonly seen in cancer. A growing number of studies have shown that increased ab initio synthesis of fatty acids in tumor cells is a prominent feature in the development of cancer. And the activation of ab initio synthesis is negatively ...
Life is all about working out. Moderate exercise not only strengthens the body, but also improves the metabolic state and slows the progression of diseases. However, different times of exercise may have different impacts, and it is an intriguing scientific question how to determine the best time to exercise. Although the influence of exercise on energy metabolism is well recognized, there is ...
A lack of oxygen can force many organisms to enter into recoverable hypometabolic states. To better understand how organisms cope with oxygen deprivation, our laboratory previously had shown that when challenged with anoxia, both the nematode Caenorhabditis elegans and embryos of the zebrafish Danio rerio enter into suspended animation, in which all life processes that can be observed by ...
The sigB gene of Corynebacterium glutamicum encodes a group 2 sigma factor of RNA polymerase. Under conditions of oxygen deprivation, the sigB gene is upregulated and cells exhibit high productivity of organic acids as a result of an elevated glucose consumption rate. Using DNA microarray and quantitative reverse transcription-PCR (RT-PCR) analyses, we found that sigB disruption led to reduced ...
The diversity and distribution of a bacterial community from Coffee Pots Hot Spring, a thermal spring in Yellowstone National Park with a temperature range of 39.3 to 74.1°C and pH range of 5.75 to 6.91, were investigated by sequencing cloned PCR products and quantitative PCR (qPCR) of 16S rRNA and metabolic genes. The spring was inhabited by three Aquificae genera—Thermocrinis, Hydrogenobaculum, ...
Secondary metabolites, or biochemical indicators of fungal development, are of intense interest to humankind due to their pharmaceutical and/or toxic properties. We present here a novel Aspergillus nuclear protein, LaeA, as a global regulator of secondary metabolism in this genus. Deletion of laeA (laeA) blocks the expression of metabolic gene clusters, including the sterigmatocystin ...
Secondary metabolites, or biochemical indicators of fungal development, are of intense interest to humankind due to their pharmaceutical and/or toxic properties. We present here a novel Aspergillus nuclear protein, LaeA, as a global regulator of secondary metabolism in this genus. Deletion of laeA (laeA) blocks the expression of metabolic gene clusters, including the sterigmatocystin ...