Metabolic State Articles & Analysis
9 articles found
The acetylation of these lysines reduces the histones' affinity for the negatively charged DNA, leading to a more relaxed, open chromatin structure. This "euchromatin" state allows transcription factors and RNA polymerase to access the DNA, thereby activating gene expression. ...
One essential approach to studying cellular metabolism is Metabolic Flux Analysis (MFA), a powerful tool that reveals the intracellular activities and metabolic dynamics of living systems. ...
Nicotinamide adenine dinucleotide (NAD) and its reduced form (NADH) are essential coenzymes involved in a wide array of cellular metabolic processes. As critical mediators in oxidation-reduction (redox) reactions, NAD/NADH plays a pivotal role in energy production and cellular metabolism. ...
The Importance of Exosome Lipidomics and Metabolomics The term lipidomics refers to the study of lipids in biological systems, whereas metabolomics involves the profiling of metabolites, the small molecules generated during metabolic processes. In the context of exosomes, these two analytical fields reveal a wealth of information about the state of the parent ...
Beyond their roles in blood flow regulation and inflammation, SMECs contribute to metabolic functions within skeletal muscle. They participate in the uptake and delivery of glucose and fatty acids, influencing the metabolic state of the muscle. This function is particularly important in the context of metabolic disorders such as ...
Moderate exercise not only strengthens the body, but also improves the metabolic state and slows the progression of diseases. However, different times of exercise may have different impacts, and it is an intriguing scientific question how to determine the best time to exercise. Although the influence of exercise on energy metabolism is well ...
Their relative population size is dynamic, depending on the state of the body (inflammatory bowel disease, diabetes, etc.). The intestinal microecosystem is rich in various compounds secreted by the host, such as glycoproteins, saliva, gastric juice, bile salts and mucus, and consumes about 1.5 kg of amino acids, short-chain fatty acids and dietary fiber from the daily diet ...
Abstract Class 1 plant hemoglobins (phytoglobins) are upregulated during low-oxygen stress and participate in metabolism and cell signaling via modulation of the levels of nitric oxide (NO). We studied the effects of overexpression and knockdown of the class 1 phytoglobin gene in barley (Hordeum vulgare L.) under low-oxygen stress. The overexpression of phytoglobin reduced the amount of NO ...
The whole‐body content of THs, the histology of thyroid follicle epithelial cells, the activities of hepatic iodothyronine deiodinases (IDs), and the transcription of selected genes associated with TH synthesis, transport, and metabolism were analyzed. Following exposure to MC‐LR, whole‐body concentrations of both thyroxine (T4) and triiodothyronine (T3) were significantly ...