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Metabolism Analysis Articles & Analysis
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One essential approach to studying cellular metabolism is Metabolic Flux Analysis (MFA), a powerful tool that reveals the intracellular activities and metabolic dynamics of living systems. ...
Consequently, NAD/NADH analysis is a cornerstone of metabolomics research, providing critical insights into metabolic health, mitochondrial function, and disease pathogenesis. In this article, we will discuss the science behind NAD/NADH, their role in metabolism, and the significance of precise NAD/NADH analysis in various ...
Enantiomeric Purity and Chiral Drug AnalysisOptical activity analysis is the standard method in the pharmaceutical industry for determining the enantiomeric purity of drugs. Since different enantiomers can have very different pharmacological activities or metabolic properties, this analysis is critical for the safety and effectiveness of ...
In medical science research, it is hoped that analysis to identify abnormal metabolic pathways and characteristic biomarkers closely related to diseases will provide a basis for further elucidation of disease pathogenesis. ...
Unveiling the Intricacies of Bile Acid Analysis Within the realm of advanced diagnostics, the analysis of bile acids stands as a pivotal technique that offers insights into liver health, digestive efficiency, and metabolic balance. ...
The steady march of progress looks different to all, but in his doctoral dissertation Sam Bickley, Ph.D., measured the effect that a certain type of progress is having on tidal creeks. Rapid development along coastal areas, particularly residential and suburban expansion, can have significant implications for the surrounding environment. While existing protections and conservation efforts can ...
Her team's imaging shows how the metabolism of the mouse brain changes when glycolysis is blocked in neurons. "This neuroimaging approach provides unprecedented information on brain metabolism," Chaumeil said. "The promise of metabolic imaging to inform basic biology and improve clinical care is enormous; there is still much to be explored." ...
The researchers further investigated the role of these microorganisms in the conversion of free sugars into energy using integrated metabolomics and metabolic reconstitution analysis. Studies have found that the main fermentation products in the intestine of dolphins are short-chain fatty acids (SCFAs), which are the main energy source of the host, indicating ...
Secukinumab, an IL-17A sequestering agent used in treating psoriasis, was selected as a repurposed candidate to address the sequential inflammatory disorders that follow the first metabolic insult. Conclusions Our analysis suggests this novel combinatorial therapeutic approach inducing DPP4 and Il-17a suppression has a high likelihood of ameliorating a ...
Taxonomic and functional analyses of gut microbiota showed significantly higher cecum bacterial diversities and abundances including genus Bilophila, Dorea, and Dehalobacterium in L. fermentum KBL375-treated mice. Metabolic analysis of the cecum also showed significant changes in the levels of various amino acids including methionine, phenylalanine, serine, and ...
Y1 was isolated from the soil of a constructed wetland, and it was identified based on the 16S rDNA sequence analysis. The co-metabolic degradation of nicosulfuron with glucose by Klebsiella sp. ...
In the present study, we sought to provide an in‐depth characterization of WF metabolism in birds using in vivo and in vitro approaches. We performed a kinetic analysis of WF metabolism using liver microsomes of four avian species and found that the metabolic ability of the chicken and crow are much higher in comparison to the ...
The model shows that the microorganisms used their energy metabolism the most efficiently in the case of the guaranteed presence of the dissolved oxygen, e.g., the ultimate acceptor of the electrons in the electron transport chain. ...
At high exposure concentration gene expression was mainly affected by inhibiting chitinase activity, inducing an oxidative stress response, and stimulating energy metabolism. KEGG pathway analysis, furthermore, implied that the high concentration may have caused impaired light sensitivity, angiogenesis, olfactory perception, learning and memory. ...
The aim of this work is to analyse exergetically the glucose metabolism, which involves the steps of Glycolysis, Krebs Cycle and the Oxidative Phosphorylation. In order to achieve these goals, a methodology for the exergetic analysis of metabolism is presented. The exergy value of the metabolic compounds takes into account the ...