Mitochondrial Disease Articles & Analysis
4 articles found
Consequently, NAD/NADH analysis is a cornerstone of metabolomics research, providing critical insights into metabolic health, mitochondrial function, and disease pathogenesis. In this article, we will discuss the science behind NAD/NADH, their role in metabolism, and the significance of precise NAD/NADH analysis in various fields of biology and medicine. ...
Furthermore, changes in the mitochondrial proteome may be associated with certain diseases, including neurodegenerative diseases, cancer, heart disease, diabetes, and genetic disorders.Methods of Mitochondrial Protein SequencingMitochondrial protein sequencing typically involves the following steps: firstly, ...
The main mechanisms by which ceramide regulates the development of obesity and related diseases are as follows: ceramide inhibits insulin signaling and hinders glucose metabolism; induces apoptosis; impairs mitochondrial function and induces mitochondrial autophagy. Ceramide and Cardiovascular Diseases Elevated ceramide ...
Mutations in more than 350 genes of mitochondrial and nuclear origin have been reported, resulting in mitochondrial diseases. ...