Neuropathy Pain Articles & Analysis
12 articles found
Lipids are not merely structural components of cellular membranes—they also act as powerful signaling molecules that orchestrate key physiological processes. Among the enzymes regulating lipid signaling, ENPP2 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 2), also known as autotaxin, plays a central role by converting lysophosphatidylcholine (LPC) into the bioactive lipid ...
What is diabetic neuropathy? The most common complication of diabetes is neuropathy, which is nerve damagecaused by high blood sugar. Most neuropathy affects the legs, hands and feet and usually presents as numbness, pain or tingling. ...
Long non-coding RNAs (lncRNAs) are a class of RNAs that do not code for proteins and are typically greater than 200 nucleotides in length. Studies have shown that lncRNAs are quite complex in function and play an important role in various biological processes such as development, differentiation, proliferation, metastasis, apoptosis, stem cell pluripotency, and DNA damage. Therefore, those ...
Abstract Background. Peripheral nerve injury can result in the formation of neuroma/nerve entrapment, a persistent peripheral neuropathic pain state which is often refractory to invasive interventions or medications. Therefore, there is a need in the field of pain management to develop innovative noninvasive therapy in treating post-traumatic peripheral neuropathic pain states. A new ...
INTRODUCTION After a peripheral nerve injury, fast conducting large myelinated afferent A-bcta fiber transmission diminishes over time. On the other hand, firing of smaller pain transmitting fibers such as A-dclta and C-fibcrs is enhanced. This aberrant afferent neuronal behavior is thought to be one of the main neuronal mechanisms leading to development of chronic posttraumatic peripheral ...
1. Tetrahydrocannabinol (THC) Tetrahydrocannabinol (THC) is an active ingredient in Nabiximols, a specific extract of Cannabis that was approved as a botanical drug in the United Kingdom since 2010 as a mouth spray for people with multiple sclerosis to reduce neuropathic pain, spasticity, overactive bladder, and other symptoms. Nabiximols (as Sativex) is available as a prescription drug in ...
Q. What is your background and experience in the regenerative medicine and stem cell space? How did this lead you to Regeneus? A. I have always had a passion to play a part in improving people’s health and this passion led me to undertaking a Bachelor’s degree of Medical Science at The University of Technology, Sydney (UTS). It was actually Regeneus that led me into the stem ...
Brenneman: In the tests conducted on mice, researchers found a dramatic difference when it came to reversing pain. CBD was found to be ineffective in reversing pain when researchers induced peripheral neuropathy via mechanical, or hypersensitivity to touch. ...
Q. Tell us about your role as Chief Scientific Officer at Regeneus? A. My role at Regeneus from the beginning has been to invent and develop Regeneus’ intellectual property (IP). With over 30 years’ experience as a scientific researcher spanning fields of regenerative medicine and microbiology, I have always been focused on developing and licencing technologies to solve problems. ...
Everyone at some time in their life has suffered from the throbbing, aching, and annoying pain of a headache. Headaches can be mild, or they can be severe and even debilitating. While most people experience a headache occasionally, others deal with recurrent head pain, sometimes experiencing headaches weekly, or even up to 15 or more times each month, as in the case of chronic ...
During this spring, the COVID-19 pandemic has dramatically changed every aspect of life. The business environment has changed not to mention the healthcare sector where the very foundations have been tested around the world. The news have been filled with corona topics and at times the pandemic has seemed to hide other alarming issues: for example, it has been reported in the US that ...
Believers and users of CBD extoll its benefits for inflammation, muscle soreness, pain, anxiety and a whole host of other things, including cancer. ...