Opioid Drug Articles & Analysis
4 articles found
The opioid crisis in the United States is a devastating public health issue, with over 70,000 overdose deaths annually, largely driven by the highly potent synthetic opioid fentanyl. The urgency to address this crisis has spurred the development of innovative therapies to prevent and reverse fentanyl overdoses. In this blog, we will explore the groundbreaking preclinical work on CSX-1004, a fully ...
CYP450 and Biosynthesis CYP450 involved in drug metabolism mainly includes seven important subtypes of CYP1, CYP2, and CPY3 families, especially CPY3A4. CYP3 family accounts for 28.8% of the total intrahepatic CYP450, which is an important enzyme involved in the first-pass effect of oral drugs. Many opioid analgesics can be metabolized by CYP3A4, ...
The coronavirus pandemic remains one of the top concerns within the United States. However, Johns Hopkins, and other research centers, are actively working to continue medical research in all divisions of medicine and health. Learn the ongoing studies at Johns Hopkins, what issues they are solving and how we can all make a difference. ...
The CDC estimates that opioid addiction resulted in a record 72,000 drug overdose deaths in 2017 alone. What strikes me as one of the most tragic parts of this narrative is that so many of these deaths were people who became addicted to opioids after simply seeking relief from chronic pain through prescribed drugs such as ...