Ovarian Cell Articles & Analysis
11 articles found
Human ovarian epithelial cells play a crucial role in ovarian function and have become a significant focus in cancer research, specifically ovarian cancer. ...
Alfa Cytology has launched ovarian cancer therapy development services. Alfa Cytology, a prominent services provider in oncology, has launched its cutting-edge ovarian cancer therapy development services. ...
It achieves this by binding to the adenosine A2A receptor (ADORA2A), which is expressed by various immune cells like T cells, natural killer (NK) cells, and dendritic cells (DCs). ...
Trop-2-mediated Cellular Pathways and Their Relationship with Tumors Trophoblast cell surface antigen-2 (Trop-2) is a surface glycoprotein member of the epithelial cell adhesion molecule (EpCAM) family. ...
CADM1 is involved in mediating interactions between cancer cells and immune cells, such as T cells and natural killer (NK) cells. ...
Popular cell cultures used include Chinese Hamster Ovary cells (CHO), and Spodoptera frugiperda-derived ovarian cell (SF9).2Bioreactors offer a precise control over the growth of biological organisms, allowing researchers to manipulate factors such as temperature, pH, and nutrient supply.3 This has enabled the production of more ...
The antibody can be released to partially target and attach to HER2 on cancer cells, and upon entering the cancer cells, release chemotherapeutic drugs to kill the cancer cells as well as nearby cells. ...
So far, anti-mesothelin antibody-drug conjugates have been successfully used to treat mesothelin-expressing solid tumors, including ovarian cancer, pancreatic cancer, and malignant mesothelioma; and mesothelin targets chimeric antigen receptor (CAR) T cell therapy also showed significant antitumor effects. ...
Mesothelin or MPF supplementation stimulates lung cancer growth in MSLN knockout mice, which verifies the role of mesothelin in tumor cell adhesion, migration, and metastasis. Role of mesothelin in cancer and signaling Mesothelin is expressed in many solid tumors, most commonly in mesothelioma, epithelial ovarian, and pancreatic cancers, as well as in lung and ...
Further studies of other solid tumor types, including pancreatic, ovarian, and lung cell lines, showed the same results: the resistance to CAR-T cell therapy stems from the loss of interferon pathway genes. "We found that CAR-T cells did not bind to glioblastoma cells that lack interferon signaling," Larson ...
Recently, in a study published in Molecular Cancer Therapeutics entitled "Olfactory Receptor OR2H1 is an effective target for CAR T cells in human epithelial tumors," scientists from Moffitt Cancer Research Center identified a novel potential target for CAR-T cells called OR2H1 through research, which may help inhibit the growth of lung and ...