Pancreatic Ductal Articles & Analysis
4 articles found
So far, anti-mesothelin antibody-drug conjugates have been successfully used to treat mesothelin-expressing solid tumors, including ovarian cancer, pancreatic cancer, and malignant mesothelioma; and mesothelin targets chimeric antigen receptor (CAR) T cell therapy also showed significant antitumor effects. ...
Role of mesothelin in cancer and signaling Mesothelin is expressed in many solid tumors, most commonly in mesothelioma, epithelial ovarian, and pancreatic cancers, as well as in lung and uterine malignancies and bile duct cancer. ...
Pancreatic cancer is a highly malignant digestive system tumor, and the five-year survival rate of patients after diagnosis is only about 10%. ...
Pancreatic cancer is at an advanced stage when diagnosed when cancer cells have spread and are hard to control. The most frequent pancreatic cancer is pancreatic ductal adenocarcinoma (PDAC), accounting for 90% of all pancreatic malignancies. ...