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Pharmaceutical Process Development Articles & Analysis: Older
45 articles found
In vitro permeability assay kits play a crucial role in the field of pharmaceutical development, particularly when evaluating the absorption characteristics of drugs. ...
In the rapidly evolving world of biotechnology, synthetic peptides have emerged as a pivotal component with wide-ranging applications in medical research, diagnostics, and therapeutic developments. These lab-created sequences of amino acids mimic naturally occurring peptides and are instrumental in advancing scientific discoveries and pharmaceutical innovations. ...
In the ever-evolving world of pharmaceutical development, the quest to innovate and improve the delivery of drug substances remains a top priority. ...
HCPs are purified together with the target product during the production process and cannot be removed. Risks of HCPs In general, HCP constitutes the major process-related impurity in the drug product in addition to the target protein. ...
Ongoing research and inventions in the field of oncology focus on the development of small molecule drug therapies for use in brain tumor resection. Small molecule drugs are being developed to target and effectively treat brain tumors to improve therapeutic outcomes. Small particles containing compounds that can enter cells and interact with specific targets to inhibit or modulate their ...
The intestinal flora is involved in many physiological and pathological processes in the host, including digestion and absorption of food, metabolism of certain nutrients and pharmaceutical compounds, development of host immunity, intestinal inflammatory states, and more. ...
Huateng Pharma, a leading Contract Development and Manufacturing Organization (CDMO), is proud to announce the launch of its latest product, Piroctone Olamine (CAS: 68890-66-4). This addition underscores Huateng Pharma’s commitment to providing high-quality pharmaceutical ingredients to meet the diverse needs of the global health and personal care industries. Piroctone Olamine is a highly ...
Pharmaceutical Stability Analysis Pharmaceutical stability analysis is a key aspect of pharmaceutical development and quality control. ...
Microspheres play a crucial role in the field of pharmaceuticals, biotechnology, and materials science due to their unique properties and applications. These spherical particles, ranging from a few micrometers to several millimeters in size, have a wide range of uses, including drug delivery systems, cell encapsulation, and as supports for various chemical reactions. Polymeric microspheres, ...
This scientifically recognized process leads to fewer gastrointestinal issues, including gas and bloating. ...
Patient-centric drug development is a divisive concept. Dismissed as a buzzword by some. Adopted extensively by others. ...
In the world of pharmaceuticals, developing safe and effective drugs is a complex and time-consuming process. ...
Carfilzomib, a proteasome inhibitor, is indicated for the treatment of patients with multiple myeloma. Multiple myeloma (multiple myeloma, MM) is a malignant tumor originating from the B cell lineage, characterized by the clonal proliferation of malignant plasma cells in the bone marrow microenvironment, causing fractures and bone marrow failure, and is the second most common blood system ...
According to the latest IDF Diabetes map, the global prevalence of diabetes reached 10.5% in 2021, with 537 million adults living with diabetes. China has become a disaster zone for diabetes, with the largest number of adults with diabetes in the world. In the past 10 years (2011-2021), the number of people with diabetes in China increased from 90 million to 140 million, an increase of 56%. The ...
Success doesn’t just come from a winning idea or an exciting new concept. Success comes from having a dedicated team behind that idea, with the enthusiasm and commitment to drive it from concept to clinic. ...
Before human testing is even considered, new drugs are developed in the laboratory. This can be a difficult process considering what illness is being targeted. You can read more about bacteria and viruses and how they are treated here. Modern pharmaceutical development focuses not only on a new cure itself but also on ...
In the passive drug loading method, the drug is encapsulated in liposomes during the preparation process. In the active drug loading method, the drug is loaded into intact liposomes. ...
Liposomes are a novel drug delivery system (DDS). They are bimolecular vesicles that form spontaneously when phospholipids are dispersed in water. Liposomes vary in size, composition and charge and can be used as carriers for a wide range of drug molecules, such as chemotherapeutic agents, antimicrobial and antiviral drugs, antiparasitic drugs, genetic material, vaccines, therapeutic proteins, ...
Canagliflozin is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. Mechanism action of Canagliflozin Canagliflozin is a sodium-glucose cotransporter (SGLT2) inhibitor. Glucose filtered in the renal tubular lumen is ...
To do so, though, requires shifting these ideals from mere concepts into actionable processes without setting an unrealistic bar for developers. Before we can expect progress, we must clearly define what we mean when we talk about transparency of ML, and articulate the practicality of doing so without leaking proprietary information. ...
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